My wife is over 50 and got her first migraine about 4 months ago. Her last episode is going on 8 weeks now with no relief. She was hospitalized 2 weeks ago, mri and ct normal. Sent home with Neurontin, Dilaudid, xanax and the headache she came in with. Dr added promethazine for nausea and 1 week later changed med to Nortriptyline. She had been on Tamoxifen which can cause headaches; it has been DCd with no change. Is it unusual for someone to start getting migraines after 50? Anyone used Nortriptyline? How long to work?