I am on 125mg per day and have no majorside effects to speak of - I'm 5'3" and my weight is fine for my height and bone frame. For me, it has been a miracle drug and my current dose is what is needed to control my migraines. It is true that there is a huge amount of negative out there on the internet about it and to read it, you would think that anyone who takes topamax is destined to turn into some kind of drooling idiot who couldn't recite the alphabet if they tried. I think that is because most people with a positive experience don't bother to post about it.
Everyone is different. Some people can't tolerate it at all, others tolerate it very well if they can find the correct dose. Many of the side effects go away after your system adjusts. The only one that has really lingered for me is that I can't drink soda - I can't sense carbonation at all and it tastes funny. Not a big loss there. I don't feel particularly tired, any more than any other busy mom of 2 kids does and I don't notice any memory problems. When my dose changed, I did have some fatigue for a few days, but it went away after my body adjusted. I had a little of the tingling hands/feet thing but certainly nothing that could ever be termed more than a minor annoyance. I also lost some weight, pretty much dead on the 10% of body weight that is the average. I've been at this dose since July.
I was started at 25mg at night for a week. Then add 25mg in the morning for a week. Then add 25mg at night so that you are taking 50mg at night and 25mg in the morning for a week. At the beginning of the 4th week, add 25mg to the morning dose. By the 4th week, you will be at 100mg per day - 50mg am and pm, which is the average dose for migraine treatment.
Fibromyalgia, High BP, Migraines, anxiety, Non Celiac Gluten Intolerant
Current medications: Topamax, Maxalt, Lotrel, Wellbutrin