I had to stop taking Topomax. I tried it twice. The first time I had what I call "stumble tongue". My words would literally get stuck and my tongue would get all twisted. Short term memory was shot. I felt stupid ALL the time.
Second time taking it ... same as above and in addition (higher dose) I was totally apathetic about everything. No energy. I wasn't really depressed, just didn't care about anything and was super tired.
I work full time and have two very active kids ... tired and apathetic didn't work out to well for me. Neither does searing migraine pain but it wasn't really helping that very much either.
Good luck ... I hope it works for you. I know it does work well for some.