First off, let me say that Shafreeka you are not alone. I think that making use of this forum is a great step (I just joined now) to getting support from people who understand what you - and I - am going through. Second, I am so humbled at the fact that there's people that are much, MUCH worse off than I am. I get weekly migraines, always debilitating sometimes more serious than others. I've been hospitalized many times...I won't bore you with my history but, like you, I have tried many medications, different "cures" (acupuncture chiropractors, naturopaths, bio-feedback, botox injections...) and nothing seems to really work. I would suggest trying to stop taking meds all together and doing daily acupuncture because although I'm not a doctor, I KNOW that taking so many meds whether simultaneously or in 2 week intervals they AREN'T going to help...However, I'm aware of the horrible pain one endures during a migraine attack and know how we all hope against hope that we're going to find the miracle drug. The next one will work, the next one will be the right one. We pray, we hang on with all our might to the idea that "all you have to do is find the right drug, you just haven't found it yet". "There's something you haven't tried". The truth is, we have to find a way to deal with migraines that's sustainable. We just want the capacity to LIVE to be without pain, to function, to be reliable, to get rid of this barbarious invasion taking over our souls. You have to tell yourself "I WILL DO THIS" "THIS WILL WORK" "I'M GOING TO GET BETTER". You have to put everything you've got into it. You've got to say: "NO! YOU WILL NOT TAKE OVER MY LIFE, I WILL BEAT YOU". We need to accept that it's a struggle, it's a battle. You're going to lose some, but you're going to win some. It might never be you are him, but eventually you will win more often and who knows, maybe you will be able to just say that migraine has been defeated. But until that day, and always look to that day, you've got to keep hope and fight with all you've got. I don't mean fight by bombarding you body with large doses of chemicals every day and changing them every few weeks (not that I think meds are altogether bad, I think they're often necessary), but fight with your mind, with your head, meditate, do yoga, get acupuncture, eat the right foods, exercise, be healthy, do introspection...put all the odds on your side, and that's the best you can do. I also pray that one day they'll find a miracle cure and be pain free forever. But until that day comes, we've got to fight for ourselves. I don't claim to have the answer, or that I know any more about migraines than any of you but I know that we're in this fight, and we're in it together.