I've had a headache since November 2012. I finally was able to see a neurologist earlier this year for it and the trigger incident was a hemiplegic migraine and after I described the last two years, he said that the headache I've had since then has been a migraine (of varying strengths).
Despite numerous medications over the last few years and the one I'm on now, it's still here. So, I guess I can't really offer much constructive advice, BUT I have found that going with lifestyle changes can improve physical ailments (adding vitamin D can sometimes help with inflammation, etc) so that's something worth looking into I think.
Chamomile tea is supposed to be good for migraines. I drink a cup of it every day, usually when I know that I may be exposed to something that'll trigger a worsening of my headache. Maybe that's something your brother might be interested in trying.
Nerve Pain, Chronic Fatigue, Muscle Pain/Weakness, Heat and Light Sensitivity, Dizziness, Immobility, Joint Pain
Never, EVER get sick. :)
Zonisamide (for migraines supposedly), Nortriptyline (for nerve pain supposedly), vitamin D, vitamin B-12, vitamin K-2, and a Prenatal.