I've been on both, and got off both. The topamax definitely helped but had a lot of negative side effects. With the gabapentin, I was unable to maintain the necessary dose (1800-2400mg/day) due to side effects. At one point I was on Topamax, Lyrica, and Gabapentin, but I've gotten off all of them because the side effects were worse than the benefit. I'm getting Botox shots now.
As a side note, many of my initial side effects from Topamax (e.g., tingling/numbness in hands and feet) went away within a month or so. The brain fog that set in was debilitating though. I couldn't think straight, had a hard time focusing, etc.
30s female. Crohn's ileocolitis dx2/06. Proctitis dx 10/12. Arthritis dx9/09. GERD dx1/13. Asthma dx4/13. Raynaud's. Chronic headaches. Chronic chest pain. Anxiety.
Meds: Remicade every 6 weeks (since 4/13), 4.8g Lialda, 75mg Trazadone, 50mg Zoloft, Klonopin, Botox for migraines, Zyrtec, Maxalt
Pentasa, Pred, Entocort, PPIs, Topamax, Lyrica, Gabapentin