I am 51 and have been having migraines since age 40. My doctor will not prescribe to me more than 4 pills per month for Imitrex due to the statement provided by the drug company that the safety has not been tested for more than 4 headaches treated per month.
However, I am taking more than 4 per month due to getting them from a friend (unusual situation), and it is keeping me working. I try to limit the number of pills for a headache. I limit the number of pills in order to avoid rebound headaches. I do not take more than one Ibuprofen pill at a time, also. I also take Butalbitol (also called Fioricet) and limit that to one at a time, too. I try the ibuprofen and butalbitol first, and if I feel the migraine coming strong, then I'll take a 50 mg. Imitrex.
I'll take one Imitrex and wait; sometimes I have to wait 4 hours before it will kick in, but it does, except one time last month--it was the first time 50 mg. did not work; and that headache was bad (may have been a rebound headache). Also, I work on several types of migraine triggers when I get one in order to kill the headache. (I have read that it takes a certain amount of one or more triggers to produce a migraine.):
1. I work with food triggers as well--cutting them out completely, caffeine, chocolate, nuts, sulfites, nitrates, citrus, aged cheese, yogurt, soy, onions, all that stuff--in order to ensure I don't have severe headaches.
2. I also do things to reduce stress.
I wish they would f-ing test Imitrex so we can have the medicine we need! Maybe they did test it and they don't want to produce the results to the FDA. This stuff is powerful and I don't want to mess with my brain, but here I am doing it...