I have had migraines for about 20yrs. I have been using imitrex injections regulary, as well as assorted painkillers and anti-emetics. My quality of life has greatly improved. The last injection I game myself became swollen and itchy. I am afraid of becoming allergic to Imitrex. Is this possible? I am also concerned with the use of pain medicine. I try alternating between darvocet and lortab so I don't keep using the same ones back to back. Of course the darvocet only takes a bit of the edge off, but it is better than nothing. Imitrex is great when I have to drive or work. I don't think I am addicted to any of the medicines, but I do depend heavily on them for relief. I read somewhere that stadol is effective and less likely to cause addiction problems. Is this true? If not, are there any others that may fit this profile?