Rebif shot~~~~next day

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Regular Member

Date Joined Jun 2008
Total Posts : 100
   Posted 7/1/2008 7:03 PM (GMT -6)   
I take my Rebif 3 x's weekly.  Alot of time the next day (say 12 to 18 hours) later I feel crappy.  I sometimes think is this worth it? nono   I know it is worth it but, I feel nasty (healthwise, that is) sometimes. skull

Veteran Member

Date Joined Mar 2006
Total Posts : 2146
   Posted 7/1/2008 7:23 PM (GMT -6)   
Hey 20 Years
Well i'm not sure of the side effects related to rebif, but do know that other meds, avonex for example, do give u the same sort of issues. Try to pre-med with maybe tylenol and then maybe continue to be on that thru the period of time u expect to feel bad. I'm so sorry u must deal with this, but u'r so's well worth it. Check out this link for the side effects u may experience.
Co-Moderator, MS Forum
*~*Sometimes the Lord calms the storm. Sometimes He lets the storm rage and calms His child.*~*
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Regular Member

Date Joined May 2008
Total Posts : 88
   Posted 7/1/2008 9:46 PM (GMT -6)   
It is a balance though- quality of life now and preventing as much future disability and progression as we can. I think both are important. How long have you been on the Rebif? I switched from Betaseron (after 4 years) to Avonex. The prefilled Avonex syringe killed the next day for me, but now I'm on the kind you reconstitute and so far not too bad. Just a little tired and sore the next day. But it's just once a week instead of every other day. So maybe if it's really becoming an issue you could try switching to Avonex or Copaxone if you haven't already. Just a thought. Talk with your doc. I got an anti-inflammatory called Diclofenac to take with my injection. Can't take regular NSAIDS because they upset my stomach. This one works well. Willow

Regular Member

Date Joined Jun 2008
Total Posts : 100
   Posted 7/2/2008 12:24 PM (GMT -6)   
Thanx so much you two. I really appreciate the help. I just love this place because now I'm NOT the only one feeling this way. I have been on Rebif 5 years. It is excellent to talk to all of you MS ppl because there just isn't a whole lot of people to talk to about this and I would have to travel so far to an MS group. Thanx gang with much love.

Forum Moderator

Date Joined Jan 2007
Total Posts : 3553
   Posted 7/2/2008 12:51 PM (GMT -6)   

I am so glad you are finding support here, Peg!  This is a great place for just that reason.  It was really nice chatting with you on Monday.  Keep posting??? 


Gretchen       co-moderator MS board       diagnosed with MS July 2006

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