I think it can get very overwhelming dealing with a new diagnosis, and then to have to make this kind of decision on top of it would make anyone’s head swim. I just want to let you know that you are not alone, and that many people on this board have been in a similar position.
Have you asked your neuro if he/she has a second choice med recommendation, should you decide not to go the Tysabri route? With regard to the CRABs (Copaxone, Rebif, Avonex, Betaseron) there doesn’t really seem to be a clear-cut “best” med out there. If your neuro doesn’t have a preference, the best med for you to start out on is the one you can tolerate and take consistently. Everyone is different, and some do better on a particular med than others. Unfortunately you won’t know how you personally will do, until you try one out yourself. However, you might look at factors like how often you have to take the medication, potential side effects etc. as you make your decision.
Also, it is not all that uncommon for people to switch therapies at some point. Your neuro will monitor how you do on the med, and if it doesn’t look like it is the right one, he or she might switch you do a different therapy. Okay, I’ve probably just made your head swim even more now (I know I’ve confused myself ;-)), sorry about that.
I see that you mention wanting to chat with other people who are on these meds. I wanted to let you know that we actually do have weekly MS chats each Monday at 4 pm pacific, 5 pm mountain, 6 pm central, and 7 pm eastern time. Unfortunately that would be the middle of the night for you there in the UK, but if you happen to be a night owl you are more than welcome to come join in.
Hang in there, and yes, please do come back and let us know how you are doing. Sunny