I remember you posting here before. You have a tragic story here. I am afraid that of course we cannot help you with a diagnosis. It seems that he has received both lyme and MS as a diagnosis? I do know that MS causes pain and for some, that pain is severe. I know that MS causes word retrieval problems and depression. I am not sure I have heard of anyone having the problems your brother is having; the extreme cognition issues, the changed speech patterns (beyond just your basic word formation). Certainly there IS a ton of variation person to person in both MS and chronic lyme. I suppose that "argumentative" can come from depression and anxiety. If I were you, I would continue to press both neuroligists for MS and a LLMD for treatment. See what each says and what they offer as treatment.
You are correct; MS and neuro/chronic lyme are very difficult to distinguish.
Is your brother on a progression therapy for MS? If he does in fact have MS, it appears to be progressing rapidly. You may also want to press for a neuro-psych testing. This can test for specific areas of cognitive functioning. Good luck!
Gretchen co-moderator MS board diagnosed with MS July 2006
I have no lesions on my soul and so I will live with no limits.