taking aspirin for fatigue

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Regular Member

Date Joined Mar 2006
Total Posts : 75
   Posted 2/9/2009 3:59 PM (GMT -6)   
my doctor put me on aspirin for fatigue. There was a study done at the mayo clinic that showed some people having less fatigue when on aspirin.
So I am taking it, on my doctors request. Sounds weird to me, I don't think it is working but I have only started a few days ago. Anyone else on it or has done any research about it? Thoughts on it?

Regular Member

Date Joined Jan 2009
Total Posts : 38
   Posted 2/9/2009 6:43 PM (GMT -6)   
Hi Anitalynn,

I haven't heard anything about the study, but I guess it makes a little sense. If aspirin helps with inflammation, then maybe it helps with myelin inflammation and reduces the effort brain impulses need to work. Let us know how it works!
Stay at home Mom
wheat / dairy free & organic since 2007 -- amazing difference!
Diagnosed with RR MS 11/2001
Copaxone and starting LDN
Andrea :)

Regular Member

Date Joined Apr 2006
Total Posts : 388
   Posted 2/10/2009 11:58 AM (GMT -6)   

Here is what I found from the Mayo Clinic.......

A randomized controlled crossover trial of aspirin for fatigue in multiple sclerosis

D. M. Wingerchuk, MD, FRCPC, E. E. Benarroch, MD, P. C. O’Brien, PhD, B. M. Keegan, MD, FRCPC, C. F. Lucchinetti, MD, J. H. Noseworthy, MD, FRCPC, B. G. Weinshenker, MD, FRCPC and M. Rodriguez, MD

From the Department of Neurology Mayo Clinic, Scottsdale, AZ (Dr. Wingerchuk) and Rochester, MN (Drs. Benarroch, Keegan, Lucchinetti, Noseworthy, Weinshenker, and Rodriguez), and Department of Biostatistics (Dr. O’Brien), Mayo Clinic, Rochester, MN.

Pharmacotherapeutic options for multiple sclerosis (MS)-related fatigue are limited. Thirty patients were randomly assigned to aspirin (ASA) 1,300 mg/day or placebo in a double-blind crossover study. Results favored ASA for the main clinical outcomes: Modified Fatigue Impact Scale scores (p = 0.043) and treatment preference (p = 0.012). There were no significant adverse effects. The results warrant further study and support a role for ASA-influenced mechanisms, perhaps immunologic, in the generation of MS-related chronic fatigue.

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