I cannot say that I've been where you've been but drawing on my experience with this illness I can say that there is always hope. It can get better, that's what's so... miraculous... interesting... scary, about this illness. It can get better. The most amazing thing though, I think, is how much I've realized that we can stand, how much people can live, through, get through, and come out on the other side of.
Have faith that your life can take shape around this new obstacle and still be a beautiful one. Remember to let people into your life. People can be much more understanding than we give them credit for sometimes and there are some truly amazing, open hearted people out there.
You say you've burned some bridges, and reaching out to these people again, rebuilding, or making new alliances is hard but reach out, don't let MS stop you from living and loving, you CAN do both of these from a chair.