Progressive meds

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ppm guy
Veteran Member


Date Joined Apr 2010
Total Posts : 1197
   Posted 4/28/2015 6:19 PM (GMT -6)   
Hi all,
The annual neurology meeting on April 24, had some interesting highlights.
A clinical trial being conducted in France by Med day. They are testing high dose biotin.
Google MD1003

The stage 3 trial had some significant findings for primary and secondary progressive ms.

After 9 months 80% of patients on the active drug had no progression, and 13% had a 1 point reversal on the edss scale. This could be the 1st maintenance drug for progressives. optic neuritis had significant improvements..

Gretchen1
Forum Moderator


Date Joined Jan 2007
Total Posts : 3565
   Posted 4/30/2015 7:23 AM (GMT -6)   
Thank you for sharing this!! This seems like great news. I am interested in this and want to know more!!
Diagnosed with MS July 2006

I have no lesions on my soul and so I live with no limits.

AnnieInArizona
New Member


Date Joined Oct 2014
Total Posts : 11
   Posted 5/1/2015 2:47 PM (GMT -6)   
Any idea of dosing?

ppm guy
Veteran Member


Date Joined Apr 2010
Total Posts : 1197
   Posted 5/2/2015 3:19 PM (GMT -6)   
    they used 300mg doses. 
 
   its mode of action influences 2 targets;
 
  1.  it activates acetyl-CoA carboxylases. the enzyme needed in synthesis of fatty acids needed for myelin synthesis.
 
  2.  it activates the Krebs cycle in demylinated axons, that increase energy production of nerve impulse.
 
 
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