I just have a couple questions I'm hoping you can answer. I was wondering If any of you have received a faint positive Lyme Disease test however it was positive because of MS?
My Lyme Disease results are:
My Lyme IgG-IgM EIA (ELISA) was Reactive
My Lyme IgG Western Blot was Non- Reactive
My Lyme IgM Western Blot was Weakly Reactive
The Mayo Clinic website states:
Diagnosing Lyme disease
IgM assay is useful for confirming stage 1 (acute) Lyme disease. (My IgM was Weakly Reactive and my symptoms have been for 5 1/2 years so this should indicate my symptoms would not be from Lyme disease as this tests positive for NEW infection.)
IgG assay is useful for confirming stage 2 and stage 3 Lyme disease. (mine was negative and my symptoms have been 5 1/2 years so this should of been positive according to Mayo Clinic and CDC if I've had Lyme Disease for a long time like months/years)
Mayo Clinic also states:
False-positive reactions may occur with patients with other spirochetal diseases (syphilis, yaws, pinta, relapsing fever, or leptospirosis), influenza, autoimmune disorders, multiple sclerosis, or amyotrophic lateral sclerosis.
So because false positive Lyme Disease results happen with people with ms, and given mine was only faintly reactive for NEW Lyme disease infection and non reactive for LATE Lyme disease infection.... im skeptical.
What I'm getting at is my doctor is suspicious of MS. I'm doing a balance test next week (ENG). She thinks this would also help rule out inner ear problems causing my symptoms and she thinks this would help the neurologist determine MS. Did an ENG Balance test help in your diagnoses?
My doctor has started me on antibiotics to treat lyme but she wrote on the report since Lyme disease often effects large Joints (i dont have this symptom) and the nervous system she thinks doing the balance test (ENG) would be beneficial to the neurologist to help determine if my symptoms are from something else like MS or to confirm Lyme Disease.
My symptoms are off balance, light headed all the time, a lot of the time its hard to stand. Sometimes feels like I'm on a boat. Sometimes I feel faint. Grocery stores make it worse and isles. Its been 5 1/2 year with this now. And just over a year ago I started developing tingling all the way up my spine, and it happens often now. I have poor circulation/numbness in my fingers and I'm always tired.
I have had 3 MRIs over the last 5 years which have been normal however my last MRI showed white matter spots at the front of my brain.
Whether its Lyme Disease or MS, or something else... I just want to figure it out! And it looks like I'm getting somewhere finally. Its been so long with no answers :( I'm just trying to make sure I get the right diagnoses so I can be treated appropriately and help myself for me and my kids.
Sorry for the long novel.
ETA : More of what is confusing to me is what the CDC has on their website. This is exactly my situation, I've been having symptoms for 5 1/2 years but my IgG is negative and my IgM is only faintly positive.
CDC website says :
I have been sick for a few years with joint and muscle pain, fatigue, and difficulty thinking. I was tested for Lyme disease using a Western Blot test. The “IgM” Western Blot test was positive but the “IgG” Western Blot test was negative. Is Lyme disease the cause of my symptoms?
Answer: Probably not. First, you should only have an immunoblot (such as an FDA-approved Western Blot or striped blot) test done if your blood has already been tested and found reactive with an EIA or IFA.
Second, the IgM Western Blot test result is only meaningful during the first four weeks of illness. If you have been infected for longer than 4 to 6 weeks and the IgG Western Blot is still negative, it is highly likely that the IgM result is incorrect (e.g., a false positive). This does not mean that you are not ill, but it does suggest that the cause of illness is something other than the Lyme disease bacterium. For more information, see the in-depth discussion regarding testing for Lyme disease.
Why does this all have to be so confusing
Lyme Disease? MS? Something Else
Post Edited (JessicaMommy) : 5/23/2015 6:07:12 PM (GMT-6)