I was diagnosed with PPMS in October, 2016. Per neuro's orders, I did manual injections of Copaxone 40mg 3x per week for the months of November & December. I had no instructions except the package insert (I knew nothing abut Shared Solutions at the time). I injected into my abdomen areas and the only reactions I had were lump/swelling at injection site, redness, itchiness - nothing I couldn't handle. In January, I discontinued Copaxone because I couldn't afford the high cost and didn't plan to return to the neuro because I really didn't like him, couldn't understand him when he spoke, confused me so much that I found out that I understood the complete opposite of what he said in later visits. In preparation for a hearing of my disability claim, I saw him again in June and he wanted me back on Copaxone. I did my own research and found SS and was able to get financial assistance. Now I am back on Copaxone (same dosage as before) using both manual and Autoject. After 13 injections, I have now had 3 BAD IPIRs. I got chills so bad that my teeth chatter, body aches, esp in legs, that feel like the flu, and the most awful headache. I actually thought I had had every kind of headache there was to have, but this is a new one for me. It starts in the back of my neck at the nape and reaches over the top of my head to my forehead. The chills and aches come on about 30 minutes after I inject. The chills go away in about 1-2 hours, the body and head aches last much longer. I spoke to SS this morning after the latest event which was last night. She recommended I speak to my neuro before I inject again. He won't be back before Aug 28th!! He goes out of the country a lot and my wait time to see him for a regular appointment is FOUR HOURS!! See why I don't like him?! I made an appt in June to see a different neuro, but the soonest she can see me as a new pt is October! Do others have such difficulty getting in to see a neuro? I get so angry when I think of how this guy just prescribed the med and basically showed me the door with no instruction or support. Neither he nor his staff mentioned (or maybe don't know about) Shared Solutions, which I find inexcusable. I have tried different injection sites with both manual and autoject injections. There is no pattern and the severe IPIR does not happen every time. I'm going to contact my PCP tomorrow to get his take on the situation, but I probably won't inject again until I speak to the dreaded neuro - and who knows how long that will be before I can actually reach him when he does return. i'm thinking he'll want me to come in (who knows when I'll get an appt) (and wait 4 hours) to see him. I'm sorry this is so long. I needed to vent to people who have experience with Copaxone and MS.