Well i cant say for others, but after months of testing and seeing a neuro surgeon and no feeling better I insisted on the LP. Well it came back normal, no OG Bands. But on other sites and doing research, and talking with others that have been diagnosis, not all the time do the OG bands show up in the first LP. I have a friend that has had MS for 12 yrs, he the OG bands did not show up on the LP until his 5th one. But his neurologist, started him on the meds before the LP was positive, he for the most part is doing well, still walking, of course he has the usual problems every now and then, but starting on the meds slowed the progressions at least for him.
I have an appt at the mayo clinic in AZ on the 25th of this month for what i was told "a week long of testing" hopefully to get some sort of diagnosis, so i know what im dealing with and can get the appropriate meds for whatever is making me sick. It will be over a yr that I have been ill and over a yr since my last LP, im going to ask them whether or not another LP is needed if they say no then im gonna go with what they say.
I had asked the neuro if a LP was necessary when i first saw him, he said no. Lets do a few more test and see the neuro surgeon. After all of them came back normal he decided to go ahead and order the LP. Give input to your DR and see what he/she says, If your not totally happy suggest an LP. As for me, I was very nervous and scared about the LP. My imagination kept picturing me leaning over the table and them digging to "find" the right spot. But when i got there, the dr went over exactly what he was going to do, and there was an x-ray machine to guide him to the right location. (what a relief) Felt like a small bug bite, but hey my skin feels like that alot anyhow lol. And he kept on talking to me the whole time to get my mind off what he was doing. I did the night before overload on caffeene, i was told that taking alot of caffeene before and when your allowed to drink after the procedure will help with the headache. Which as soon as I got in the car after the 2hr wait after, i had to frappachino's and chugged them to help even more. Thank goodness i didnt get the sever headache that some people get.
Well i think i have rambled on enough. I hope your appoint when you get it goes well and you get some answers.