It doesn't sound like you've seen a doctor recently for these symptoms? 5 years is a long time between MRI's, to determine if there is something wrong. When yo go in to see your primary care doctor, take a list of the most troublesome symptoms, be sure he knows about your testing 5 years ago, and be prepared to tell him what new or worsening symptoms have occurred since then. Be prepared to undergo lots of testing, if not starting with the pcp, then perhaps with a neuro, or maybe a rheumatologist, depending on what the doctor might suggest as your first stop.
As Rhonda suggested, there is a long list of things that can cause similar symptoms, so it's impossible for anyone here to say exactly what is going on with you, but you should see a doctor and begin the testing process.
MS is not a directly inherited disease, so the fact that there isn't any MS in your family doesn't mean much. MS is an autoimmune disorder; are there others in your immediate family with things like diabetes, or lupus, or rheumatoid arthritis? Those are autoimmune disorders, too. Sometimes a tendency to have one or more autoimmune disorders can "run" in families.
Otherwise, there are plenty of folks with MS who have had the bad luck to be the first or only one in their family with such a disorder.
...I am not a doctor, nor health professional, and don't pretend to be one, here.....