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New Member

Date Joined Jun 2007
Total Posts : 11
   Posted 7/19/2007 8:52 PM (GMT -7)   
Has anyone tried Sativex?  I know it's not available in the US, but I read that the FDA may start trials on it.  I've always been skeptical of the benefits of marijuana, but I've been unable to find anything that helps with the leg pain and it's driving me crazy.  At this point I'll try anything!

Veteran Member

Date Joined Mar 2006
Total Posts : 2146
   Posted 7/20/2007 11:35 PM (GMT -7)   
Hey Mortisha!

I'm sorry, no experience with Sativex, but i see u'r having lots of leg pain? I have lots of leg pain too!! I'm currently dealing with nerve pain in almost every part and have been using Neurontin, but thinking of trying something different or maybe changing the way i'm using it for improved performance. What meds have u tried?? Some have suggested Lyrica to me. Maybe take a look at my thread "Nerve Pain" and see what some of the other suggestions have been. Best wishes to u on this. I do know how bad this can be!
Co-Moderator, MS Forum
*~*Sometimes the Lord calms the storm. Sometimes He lets the storm rage and calms His child.*~*

Zoe Butterfly
Regular Member

Date Joined Jun 2007
Total Posts : 134
   Posted 7/21/2007 4:40 AM (GMT -7)   
what is sativex??

Zoe Butterfly3
MS-- Diagnosed August 2006

Regular Member

Date Joined Nov 2006
Total Posts : 87
   Posted 7/21/2007 5:07 AM (GMT -7)   
Sativex is an oromucosal (mouth) spray developed by the UK company GW Pharmaceuticals for multiple sclerosis patients, who can use it to alleviate neuropathic pain and spasticity. Sativex is distinct from all other pharmaceutically produced cannabinoids currently available because it is derived from botanical material, rather than a solely synthetic process. Sativex is a pharmaceutical product standardised in composition, formulation, and dose. Its principal active cannabinoid components are the cannabinoids: tetrahydrocannabinol (THC) and cannabidiol (CBD). The product is formulated as an oromucosal spray which is administered by spraying into the mouth. Each spray of Sativex delivers a fixed dose of 2.7mg THC and 2.5mg CBD.

It can be bought in Canada, but confiscated at the border.
Rebif 44 mcg x 3; lyrica, ambien

New Member

Date Joined Jun 2007
Total Posts : 11
   Posted 7/21/2007 10:49 AM (GMT -7)   
Rhonda-, I tried Neurontin and Lyrica with no relief. I am currently on Klonopin at bedtime, Tegretol and Zanaflex twice a day, but there are some evenings that I just want to cry the burning, numbing pain is so bad. The other night I doubled up on the Klonopin and took an Ativan just to get some relief. I certainly feel asleep, but I can't do that every night. Short of putting myself in a coma I don't know what to do!

It's ironic that Bayer is the company that owns/distributes Sativex and we can't even get it in the US.

Post Edited By Moderator (Kimber) : 7/21/2007 2:26:44 PM (GMT-6)

Veteran Member

Date Joined Jun 2005
Total Posts : 1852
   Posted 7/21/2007 1:39 PM (GMT -7)   
Hi Mortisha,
   I'm sorry you are in such pain and the meds you've tried don't seem to work for you.  My husband was in the same kind of situation when he was diagnosed, tried everything and nothing worked. After exhausting everything she would prescribe his doctor ended up sending him to a pain management clinic and he finally got some relief.   Might be worth a try for you as well. 
    I had to edit your previous post because discussion of marijuana, even for medicinal use is against the rules of the forum.  I hope you understand. 
Co-moderator for Multiple Sclerosis
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