Avonex frequency make a difference on side effects?

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New Member

Date Joined Jul 2007
Total Posts : 5
   Posted 7/21/2007 9:02 PM (GMT -6)   
Hi all!
Just wanting to find out from other Avonex users - have you noticed any difference in your side effects if you vary the number of days between the shot?   I certainly have, and I believe it's happen to me twice - both times I was delaying giving myself the shot due to upcoming travel (didn't want to tote it with me due to refrigeration).  I had made it through the first month - every time getting easier, and felt like I was coasting.  Then I waited 9 days to take my 6th shot (as the good folks at Biogen say you can do) and wham - down for the count with the nausea, tremors, chills - well, I'm sure I don't have to tell you all, right yeah ?   BTW - my good doctor gave me Meclizine (sp?) for the nausea after my first week.  He said he thought I probably had the flu, but he'd prescribe, just in case.  I have now reassured him from subsequent shots that it wasn't the flu - LOL! 
Anyway, my point in mentioning this is that I'm really glad I listened to my RN friends who advised me to ask for some anti nausea med, as it has made acclimating my body to this much more tolerable.
So - anyone else have experience with this time between shots phenomena?  I'm trying to analyze this a bit, realizing that everyone is different.  Maybe we can all benefit...  One more question - what's the latency for everyone between shot and side effect symptom?  Mine is pretty much 5 hours on the dot, it seems.
Thanks in advance for your replies!

Diagnosed 02/07
CombiRX participant starting 05/07

Regular Member

Date Joined Dec 2005
Total Posts : 67
   Posted 7/23/2007 6:02 PM (GMT -6)   
Hi there,
I have been on Avonex for almost 2 years. I think 9 days is too long to wait. My doc said 1 day either way and I find that if I do change it I am better off if it isn't even 24 hrs difference. Traveling with Avonex is really easier than I first thought. I went to Europe last year and didn't have a bit of trouble. Just used an insulated lunch bag with a cool pack. Much less trouble to keep to the schedule than to deviate and get sicker Good luck in the future!
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