Thank you-my daughter was on a high dose of Remicade also,which she received every 4 weeks. Her surgeon never mentioned that. I will have to ask him his thoughts on that. I wish I would have asked more questions first, but it was time for her next Remicade or to switch and try another medicine. She didn't want to try another medicine and another 4 months to see if that would work and miss another summer. She has been sick for 15 months and nothing seemed to put her into remission. They did do hers in a 2 step process. She is doing great, they let her go home a day early. (Other than dealing with the bag). She has your daughters e-mail address, I have been trying to get her to write her and ask how she is dealing with it. Maybe that will come in her own time. Her GI doctor really wants her to wait a year before her takedown. She doesn't want to wait that long. That was really nice of your daughter to offer to talk with mine. Thank her for me.