I have had my ileostomy since May, and I am also on a lot of medications. I was told by my ostomy nurse that I needed to make sure what I was taking would not interfere with having my stoma. They said that I was to not take any extended-relief medications. Then before I left the hospital they checked to make sure all my meds were okay to take. However, I take over-the-counter Uriniary Pain Relief tabs on a regular basis and they sometimes will not digest all the way and will come thru into my pouch. I think what I notice mostly is that medications seem to wear off quicker for me, since they are going thru my system so quickly.
Best of luck to you.
Your Healingwell Friend,