Yeah, I had severe rectal inflammation after my sub-total colectomy. I tried Canasa and butyrate suppositories. Because it was close to my next surgery to remove the rectum all together the surgeon requested that I not use rectal steroids, but that would have been the next step.
The other option would be to switch to a maintenance med that works systemically, like 6MP or Remicade, instead of a topical like Pentasa. That would treat potential inflammation in the small bowel as well as the rectum, even though it isn't hooked up.
dx'ed UC pancolitis 5/12
past meds: asacol hd, VSL#3, apriso, rowasa, xifaxan, 6mp, cortifoam, pentasa, cimzia, canasa, butyrate, flagyl, cipro, prednisone, remicade, methotrexate, cholestyramine, cortenema
current meds: none!
step one: colectomy, end ileo 1/16/13
step two: j-pouch construction, loop ileo 5/1/13
step three: takedown 7/31/13