Imuran? Before I went from a temp to a permanent ileo I was on a combination of Imuran and Cipro to help with the rectal issues. I did not have extensive bleeding but did have varying degrees of stuff (for lack of a better word)/bowel movements. The combination worked for quite a while and I would only have a bowel movement 1 to 3 times per week (versus anytime without control).
Imuran does require blood tests and I stayed away from sick people...but it was better than the alternative. Not sure if you see a lot a patients with your position...that would have to be considered if it's a possibility.
Even though I have Crohn's my biggest flare (that lasted about
5 years with varying degrees of intensity/drugs/surgery) started within a month after I quit smoking....and I am still glad I quit