I also suffer from heart disease and underactive Thyroid so my results may, of course, prove to be different from what others experience but here goes:
The effect pf the Vitamin E seemed to be almost immediate. I take 2 Sinemet tablets (2 X 25mg/100 mg) 5 times a day. 7:00 am, 10 am, 1:00 pm, 4:00 pm and 7:00 pm. I took one 400 UI tablet of the Vitamin E (Member's Mark) at 7:00 a.m. with my first Sinemet pill.
The Sinemet usually "takes effect" within 30 minutes of that first dosage. The Vitamin E tablet seems to have delayed the effect of the Sinemet by almost 2 hours. I'm convinced it's an interaction but, of course, it's dangerous drawing too strong of a conclusion from only one test.
My normal early morning "3LT statistic" normally comes in at about
"115". After the first dose of Sinemet it drops suddenly to around "80" by 7:30 am. I feel fairly good there but feel best at "70" or less (most "healthy people" seem to have a 3LT "statistic" of about
60-70). With the Vitamin E it was almost 9:30 am before the Sinemet took effect. My neurologist seems to agree with me that the vitamins are effecting my PKD and one of the GP doctors I work with thinks it's doing something to with my heart <smile>. They're probably both right!
I plan on repeating the Vitamin E study in a few weeks.
Right now I'm looking at CO Q-10. It's giving VERY exciting results. My neurologist specifically asked that I take look at it. Be careful, though, different dosages are giving very complex results. I'll be looking at 50 mg, 250 mg, 500 mg, 750 mg and 1000 mg a day.
My results with something called "Ocuvute PreserVision" multivitamin were terrible. It made me nauseous. It dropped my "3LT statistic" but it varied wildly during the day and I experienced LOTS of dyskinesia. Oh, well.
If there was a way to attach my plots to this message I'd be glad to provide them but I'm too new at this message board to figure out how to do that!
I'm also a bit concerned about
any possible legal issues if I provide that information here but I assume that as long a I say "use at your own risk - no warranty implied or accepted" <ha> that it will be ok.
This is all very experimental data and none of it has been independently confirmed! (<whew> Have I made enough excuses, yet? <smile>)