I have been on levododpa/carbadopa about two years, which I take every 4 hours. about 15 minutes before each dose is due, I always get the same set of symptoms: pressure in stomach, pressure in head and sinuses, sinus drainage, difficulty in breathing. (None of these are severe, just very uncomfortable.) Up until two months ago, there were three additional places of pressure to add to that list: back of neck, throat, and right ear. However, I no longer experience pressure in these last three places, and I think I know what I've done to help: every morning I feel so rotten that as soon as soon as I take the first dose, I sit in a chair for 30-45 minutes until the medication kicks in. I decided I wanted to do something positive during that time to counteract the unpleasantness. So, two months ago, I started doing a gentle scalp massage each morning. Using gentle pressure with my fingers, I start with my forehead, work up to the top of my head, up the sides, down the back, and down my neck. Since starting this massage, the neck, throat and ear pressure have never come back. Maybe this could help others. (If anyone tries it and it helps, please let me know.) Now, I'm looking for non-drug ways to stop the stomach and sinus pressure. Any suggestions?
As a side note, I'd like to mention two books that, although not specific to Parkinson's, have been very helpful to me. The first is The Trigger Point Therapy Workbook, by Clair Davies. It's a self-treatment method (massage) for sore muscle pain relief when the pain comes from muscle knots caused by overuse, strain, imbalance, etc. It helped me relieve a lot of muscle pain even before I got Parkinson's. I can't help but think that these knots are also being created when our lack of dopamine creates muscle tension, rigidity, and spasm. I wish some enterprising young medical researcher would apply what's in this book to Parkinson's.
The second book is Facial Reflexology: A Self-Care Manual, by Marie-Frence Muller, M.D., N.D., Ph.D. I don't know if this method helps all the medical conditions that the author states. However, I do know that it is extremely relaxing, and I do it almost every day.