My experience of Azilect (rasagiline) has been positive
I was diagnosed in 2000 & am currently taking Azilect (1mg daily) in conjunction with 1mg of Pergolide x 3 daily. It is a fairly new drug & has only been licensed since early 2005 for use in Uk. I have been on it for approx 6 months - it was added to extend the active 'on' time of the Pergolide & help prevent end of dose tail off symtoms. I have certainly found it beneficial.
As well as being used as adjunct therapy in moderate to advanced PD I believe it is used mainly as monotherapy in early stages of PD when it is supposed to slow down the progression of the syptoms.
Ive previously taken Ropinerole & Cabergoline- neither of which I couldnt tolerate due to terrible nausea, headaches & drowsiness. Azilect is thouht to be well tolerated by most & Ive had no known side effects from it - although I have had a persistent cough which is under investigation.
I stopped taking the Azilect for a month recently to see if the cough was realated - it didnt appear to be, so Ive restarted it as I certainly noticed a decline in my motor skills when I was not taking it. Though I cant say it has done much to improve my tremor!!
Hope this helps