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Colj_uk
New Member


Date Joined Nov 2007
Total Posts : 9
   Posted 1/5/2008 3:20 PM (GMT -7)   

Thanks for all the kind posts and thanks Tony for the recomendation of Dr Charles Myers 'Beating Prostate Cancer: Hormonal Therapy & Diet. I have managed to track down a copy which makes interesting reading although my Consultant Oncologist did not agree with his tripple hormone approach but it has given me hope that there is scope to try other strategies rather than move to Chemotherapy after Zoldex and Casodex stop working. She did agree with some of his additives which I have been taking (Lycopene, Selenium and Soy isoflavones) along with green tea, red wine and plenty of exercise (running).

I have now started clinical trial and have been randomised to have Celecoxib (asprin type drug used for treating arthritis which has proved promising in lab tests) in combination with HT for a double prong attack at slowing the cancer growth.

The fantastic news is that a little after 9 weeks of having Zolodex injections my PSA level (required as part of starting the trial) has fallen from 136 to 1.0 and to 0.5 after 12 weeks (including 12 days of Celecoxib). My Consultant Urologist has advised that having a PSA lower than 3.0 indicates a better prognosis which is encouraging.

 

Thanks again, Col


Age 55
PSA prior to starting HT 136
Gleason 10 (5+5)
HT (Zoladex) started 17th Sept 2007
PSA 19th Nov 2007 1.0
Celecoxib started 7th Dec 2007
PSA 19TH Dec 2007 0.5 


Michael's Wife
Regular Member


Date Joined Aug 2007
Total Posts : 150
   Posted 1/5/2008 5:22 PM (GMT -7)   
Wonderful news! That's quite a drop! Sounds very encouraging.


Husband: Age 58
Stage: T1c
Gleason: 6 (3+3)
PSA: 4.4
Biopsy: 12 samples, Adenocarcinoma involving 3 cores, right side only (95%, 90%, 30%, discontinuously)

Pre-op prostate study - November 13
Brachytherapy - December 12, 2007
CT Scan scheduled for January 11, 2008

So far, so good!


Tim G
Veteran Member


Date Joined Jul 2006
Total Posts : 2248
   Posted 1/5/2008 5:35 PM (GMT -7)   
Col--Your PSA looks great...\O/ \O/ \O/ Three cheers!  Take care and hang in there...Tim
Age 59 PSA 2.6 (PSA velocity--quadrupled in 1yr) 1 of 12 biopsy cores positive
Bilateral nerve-sparing open RRP 6/21/06  Gleason 5
Cancer confined to prostate, post-op PSA's non-detectable


myman
Veteran Member


Date Joined Feb 2007
Total Posts : 1219
   Posted 1/5/2008 5:40 PM (GMT -7)   
Col,

What a terrific PSA response! That's great and of course, the more options the better. :-)

Continued success,
Susan
Husband Diagnosed 11/17/05 Age: 63 PSA: 7.96 No Symptoms
2/09/06: LRP - Post Pathology - Gleason 4+3 Stage T2b NO MX
3 mo. PSA: 11.8 Stage T3a
6 mo. PSA: 18.8 Stage IV Systemic w/ distant lymph node involvement
Start HT - Lupron 3 mo. shots
12/06/06: PSA 0.8
03/07/07: PSA 0.3
06/06/07: PSA 0.1
09/05/07: PSA 0.1
11/27/07: PSA 0.1


bluebird
Veteran Member


Date Joined May 2006
Total Posts : 2542
   Posted 1/5/2008 5:59 PM (GMT -7)   
tongue  Hey ~ Col,

WOW... Great News....

Thanks for continuing to stay close and getting this wonderful update to us.  Know we care ~ and we send warm thoughts and gentle hugs to you! 

In Friendship ~ Lee & Buddy

 

Threads started by: Colj_uk

Experiences of using intermittent hormone treatment

 


Doting Daughter
Veteran Member


Date Joined Aug 2007
Total Posts : 1064
   Posted 1/5/2008 8:19 PM (GMT -7)   
What a way to start off the year! We all share in your joy! Congrats!

Father's Information
DX July 15, 2007
Age 62 (now 63)
PSA 5.5
Original Gleason 3+4=7 
Post Surgery Gleason- 4+3=7
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin
One positive node
Bone Scan/CT Negative (Sept. 10, 2007)
T3a N1 M0
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07
Lupon beg. Dec 03, 2007 2 yr
Radiation soon to follow
 
 


dutchy
Regular Member


Date Joined Jun 2007
Total Posts : 75
   Posted 1/7/2008 10:05 AM (GMT -7)   
The dramatic drop in PSA is very encouraging and will improve the prognosis. Congratulations!
Dutchy's husband:
 7/6: PSA 1,946, multiple bone metastases in thoracic, lumbar spine, pelvis, bilateral ribs and proximal left tibia, 2 weeks Casodex (50 mg)
25/6: PSA 407, Lupron injection (22.5 mg) + Zometa (4 mg IV)
20/8: PSA 3,7
24/9: Started 50 mg Casodex daily
29/9: PSA 0.7
30/9: Lupron injection (22.5 mg) + Zometa (4 mg IV)
14/10: PSA 0.17
18/13: PSA 0.003, Lupron injection (22.5 mg), Testosteron 0.6
 
 
           


Mike A
Regular Member


Date Joined Feb 2007
Total Posts : 213
   Posted 1/7/2008 10:13 AM (GMT -7)   
Col,
Good news about your PSA drop! Nice way to start the new year! Keep those numbers going down, down, down!
Best,
Mike
June 2005 - Age 53 PSA 4.8 at regular physical October 2005 - After several rounds of anti-biotics, PSA 5.2 at Urlogist November 2005 - Biopsy negative July 2006 - PSA 5.9 at regular Physical October 2006 - After several more rounds of anti-biotics PSA 8.1 November 2006 - Second biopsy - Positive December 2006 - Gleason (3+4=7), Tumor T1c, CT Scan and Bone Scan Negative
January 2, 2007 Robotic Prostatectomy, University of Rochester Medical Center - Tumor confined but larger than thought, only one nerve able to be spared. Margins clear. February 2007 - Three to fo ur pads a day, no erection with viagara. April 2007 - First Post-Surgical PSA 0.02. Down to one pad a day.July, 2007 - Six Month Post-op: PSA 0.04 No change in ED. October, 2007 - Nine Month Post-op: PSA back down to 0.02!Almost totally dry! Only slight improvement in ED - Will try injections if not improved by next appointment.

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