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Danalee
New Member


Date Joined Jan 2008
Total Posts : 2
   Posted 1/6/2008 1:16 PM (GMT -7)   
My husband (54) was diagnosed with metastatic prostate cancer in May 06. It had spread to his spine, lungs, ribs, pelvis. He was given an initial dose of radiation and then started on Lupron injections (every three months) and Casodex pills daily. Recently he has started experiencing severe chest pain. His doctor has said that this could be a side effect of the combination of the two drugs. Dr. canceled quarterly hormone shot (Lupron) this week. Also his PSA levels can gone up the past two months, presently 4.0. Has anyone else experienced this chest pain and what was the solution, if any?

FLHW(David E)
Regular Member


Date Joined Nov 2007
Total Posts : 201
   Posted 1/6/2008 1:34 PM (GMT -7)   
Is the pain bone or some other type pain? Is he also on Zometa? I have occasionally experienced pain after Zometa transfusions.
Dx'd 2/18/05
PSA 219, bone mets, lymph node involvement
Gleason Score: 7
Current (12-03-07)
PSA: 21
Lupron, Keto, Avodart

Personal Blog:
prostatecancerat42.blogspot.com
www.flhw.org


Danalee
New Member


Date Joined Jan 2008
Total Posts : 2
   Posted 1/6/2008 2:30 PM (GMT -7)   
No it is just in his chest. It seems to be worse after he takes his casodex each day, we think.

myman
Veteran Member


Date Joined Feb 2007
Total Posts : 1219
   Posted 1/6/2008 3:16 PM (GMT -7)   
Danalee,

I'm so sorry you and your husband are going though this, it's a frightening and difficult time.

This is from the Casodex site:
"CASODEX is generally well tolerated (breast swelling, pain and hot flushes can occur)." And Lupron is not known to cause cardiovascular problems.
But as your physician stated, it may the the combination.
Did your husband have any heart problems previous to his treatment? He's sure to be under a great deal of stress and that adds to his pain.
I wish I could be more helpful.
Be sure to come back here so we know how you're both doing, you're in our prayers,
Susan
Husband Diagnosed 11/17/05 Age: 63 PSA: 7.96 No Symptoms
2/09/06: LRP - Post Pathology - Gleason 4+3 Stage T2b NO MX
3 mo. PSA: 11.8 Stage T3a
6 mo. PSA: 18.8 Stage IV Systemic w/ distant lymph node involvement
Start HT - Lupron 3 mo. shots
12/06/06: PSA 0.8
03/07/07: PSA 0.3
06/06/07: PSA 0.1
09/05/07: PSA 0.1
11/27/07: PSA 0.1


dutchy
Regular Member


Date Joined Jun 2007
Total Posts : 75
   Posted 1/7/2008 9:53 AM (GMT -7)   
My husband occasionally experiences chest pains but we're not sure what is causing them. It's not a side effect of Lupron, Dr. Strum stressed this when we brought up the issue at another website and it doesn't seem to be related to Casodex or Zometa either. A CT-scan and an oxygen test all came back fine, so we don't worry too much about it. I sometimes wonder whether it's stress related.

If your husband faces persistent chest pains, he should insist on getting more tests done to figure out what is causing hem. You may want to check out the website for advanced prostate cancer (I forget the name, I'm not on my own laptop). The folks out there are extremely knowledgeable.

Wishing you the best. Dutchy
Dutchy's husband:
 7/6: PSA 1,946, multiple bone metastases in thoracic, lumbar spine, pelvis, bilateral ribs and proximal left tibia, 2 weeks Casodex (50 mg)
25/6: PSA 407, Lupron injection (22.5 mg) + Zometa (4 mg IV)
20/8: PSA 3,7
24/9: Started 50 mg Casodex daily
29/9: PSA 0.7
30/9: Lupron injection (22.5 mg) + Zometa (4 mg IV)
14/10: PSA 0.17
18/13: PSA 0.003, Lupron injection (22.5 mg), Testosteron 0.6
 
 
           


dutchy
Regular Member


Date Joined Jun 2007
Total Posts : 75
   Posted 1/7/2008 10:01 AM (GMT -7)   
At www.prostatepointers.org you can post questions which will be answered by prostate cancer specialists.

www.hrpca.org is for people dealing with advanced prostate cancer and I found the folks out there very knowledgeable.
Dutchy's husband:
 7/6: PSA 1,946, multiple bone metastases in thoracic, lumbar spine, pelvis, bilateral ribs and proximal left tibia, 2 weeks Casodex (50 mg)
25/6: PSA 407, Lupron injection (22.5 mg) + Zometa (4 mg IV)
20/8: PSA 3,7
24/9: Started 50 mg Casodex daily
29/9: PSA 0.7
30/9: Lupron injection (22.5 mg) + Zometa (4 mg IV)
14/10: PSA 0.17
18/13: PSA 0.003, Lupron injection (22.5 mg), Testosteron 0.6
 
 
           

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