Update on bad post op pathology

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Bootheel
Regular Member


Date Joined Oct 2007
Total Posts : 300
   Posted 2/12/2008 8:35 PM (GMT -7)   
 Just got a call from the Uro.  Post op Gleason 7 (3+4). Better than 4+3.  One positive margin about 1mm. No lymph node involvement.  Appointment Thursday.  16 days with Mr. Hang.  Won't miss him.  Thanks for all your encouragement and support. 
Age 65
Diagnosed 10/12/07
PSA 6.3
Biopsy 18 core samples, 2 positive <5%
Stage T1a Gleason 6 (3+3)
LRP  1/29/08


Tim G
Veteran Member


Date Joined Jul 2006
Total Posts : 2249
   Posted 2/12/2008 9:45 PM (GMT -7)   
Thanks for your update on your pathology report, Joe.  What a relief that there is no lymph node involvement! 
 
I had my catheter in for two weeks.  It was nice at night because I didn't have to get up to make my bladder gladder, but was relieved to finally be rid of it.
 
On walks around the neighborhood with my dachshund, he was very curious about the urine bag strapped to my leg at his nose level.
 
Hope your appointment goes well.  Please let us know what's next for you.  Take care and hang in there...Tim
Age 59 PSA 2.6 PSA velocity quadrupled in 1 yr 
1 of 12 biopsy cores positive (5%) 
Open surgery June 2006  Cancer confined to one small area of the prostate Gleason 5
Post-op PSA's non-detectable


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8122
   Posted 2/12/2008 10:39 PM (GMT -7)   
Hi Joe,
My prayers that you PSA now drops out to undetectable. You will have more choices then. I waited until I knew mine would drop to undetectable before starting adjuvant therapy. It did, but I knew though that for me I was very high risk of return. It was like the numbers say below and it DID go to undetectable. I still am high risk but I went on a dam.n the torpedos attack and fired all of them all at it. if your can go to undetectable, you may just choose to wait or just radiation. You don't state your stage but it sounds like T3a. But I have heard of some doctors saying T2c in some light extracapsular penetration. If you could clarify that would be helpful to you in your next moves.

Tony


Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology: Gleason 4+3=7, positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (1/08): <0.1
I will continue HT until May '09. 
 
Visit my Journey at:
 
STAY POSITIVE!

Post Edited (TC-LasVegas) : 2/12/2008 11:09:20 PM (GMT-7)


biker90
Veteran Member


Date Joined Nov 2006
Total Posts : 1463
   Posted 2/12/2008 10:46 PM (GMT -7)   
Good luck Bootheel,
Like Tony said, we hope for a zero PSA so you have more choices. Please keep us posted...

Jim
Age 73. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3.
RRP 12/7/06. Nerves and nodes okay.
Catheter out on 12/13/06.  Dry on 12/14/06.
Pathological stage: T2C N0 MX. Gleason 3+4.
PSAs from  1/3/07 - 1/17/08 0.00. 
Next PSA test on 7/17/08
"Patience is essential, attitude is everything."
 


biker90
Veteran Member


Date Joined Nov 2006
Total Posts : 1463
   Posted 2/12/2008 10:48 PM (GMT -7)   
Good luck Bootheel,

Like Tony said, we hope for a zero PSA so you have more choices. Please keep us posted...

Jim
Age 73. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3.
RRP 12/7/06. Nerves and nodes okay.
Catheter out on 12/13/06.  Dry on 12/14/06.
Pathological stage: T2C N0 MX. Gleason 3+4.
PSAs from  1/3/07 - 1/17/08 0.00. 
Next PSA test on 7/17/08
"Patience is essential, attitude is everything."
 


mozart250
Regular Member


Date Joined Jan 2007
Total Posts : 102
   Posted 2/13/2008 5:05 AM (GMT -7)   
Wow you and I are comparable.  One positive margin and gleason 3+4.
 
Curiously my first post-surgery PSA was 0.1.  Then it went down to 0.0 for two readings.
 
For the last two readings it returned to 0.1.  My urologist seemed unconcerned about the 0.1, but I eventually wanted a second opinion and went to a radiologist.  We decided that if the next test were 0.1 that I would undergo radiation to kill anything that might be left.
 
I say that only to point out that you too might encounter disagreements as to the advisable course of action at this stage.
52 Year Old DBA by profession; amateur pianist by passion.
 
June 2006:  PSA 4.6.  DRE prostate enlarged.  
Aug  2006:  Second opinion confirms first.  Biopsy suggested.
Sep  2006:  Biopsy results positive one lobe.  Gleason 3+3.
Nov  2006:  RPA performed at Fletcher Allen in Burlington VT.
Nov  2006:  Pathology report: Stage T3a and Gleason 3+4.
Dec  2006:  PSA 0.1
Feb, May  2007:  PSA 0.0 (under 0.1)
Aug, Nov  2007:  PSA 0.1
 
Trying my hand at blogging.


JCL
Regular Member


Date Joined Jul 2007
Total Posts : 242
   Posted 2/13/2008 6:14 AM (GMT -7)   

Hey Bootheel,

I was a post-op Gleason 7 too (3+4), but with negative margins and negative capsular penetration. Nonetheless, I'd sleep better if I were post op Gleason 6. It is what it is so I just keep hoping and praying to remain with an undetectable PSA.

 Good luck and I'll be praying for those big fat 0s in all your follow up PSA tests.


Diagnosed: March 25, 2007. Age 49
Biopsy: Gleason 6. Five of twelve samples positive with <5% each. No perineural invasion seen.
Surgery: May 21, 2007
Post-op Pathology: Upgraded to Gleason 7 (3+4), negative margins, negative capsular penetration, negative seminal vesicles, lymph nodes left intact, multifocal perinural invasion, 15% of prosate involving cancer in both lobes. T2c
Continence: Out of pads at five weeks. Seven months post-op I'm fully continent.
Erections: Yes! With the assistance of Cialis.
Post Surgery PSA: Three tests, all <0.1
Family history: Great-great grandfather died from PC. My Father had his prostate removed at age 67 in 1997 and has had an undetectable PSA ever since. I was diagnosed at a much earlier age and had a more agressive cancer than my father. Go figure.


maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 782
   Posted 2/13/2008 5:13 PM (GMT -7)   

Hi Joe,there is a good chance that the surgeon has removed everything from the prostate bed, your post-op PSA will tell the tale, depending on that, you may have to undergo radiation to clean up anything that was left, my surgeon told me that if any cells have escaped, they are almost in all cases, confined to the prostate bed, and the radiation kills them......and then they say "in most cases" which covers thier backsides, but leaves you hanging out for that PSA!! I will know on 30th April where I stand.

All the best to you.

Regards Mal.

 


age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7  right side tumour adenocarcinoma stage T2a
RP on 30th July,
Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck, free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.
 
Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
PSA 0.5 23rd October. Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.


Bootheel
Regular Member


Date Joined Oct 2007
Total Posts : 300
   Posted 2/14/2008 8:43 AM (GMT -7)   
Hope the PSA is good news for you.  We are half way to Albuquerque in Las Cruces New Mexico.  200 more miles today.  Appointment with Uro at 3 PM.  Sure won't miss the catheter.  He will put me on some kind of therapy to get the lower half of me working eventually. He will probably work out a future plan for treatment if needed. I will also pressure him for some kind of prognosis. The information you provide is very helpful to me and I appreciate it.  Will keep you posted.
 
Joe
Age 65
Diagnosed 10/12/07
PSA 6.3
Biopsy 18 core samples, 2 positive <5%
Stage T1a Gleason 6 (3+3)
LRP  1/29/08
Post-op
Gleason 7 (3+4)
1 positive margin 1mm 

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