Hi, I'm sorry to hear that your father was diagnosed with advanced PCa. My husband was diagnosed with a PSA of nearly 2000, and the cancer had spread throughout his body (bones, lungs, etc. see signature).
It is indeed important that the PSA goes down quickly because it is an indication of how well the body responds to the hormone treatment. It will also be possible to monitor to what extend the tumor is reduced through various scans. The question that many of us are faced with is how long it will take until the cancer becomes hormone independent.
The 1-2 years is just an average and doesn't tell you much about
how reality will be for your father. Your father may be lucky and amongst the many men whose PCa doesn't become hormone independent until after 5 years or even more. Furthermore, the 1-2 years does not take into account the new types of treatment. Based on what I've read, I believe that the one year that chemo may give is too pessimistic.
There is a school of thought (Dr Strum, Dr Meyers) that strongly believes that in your father's situation the treatment should be far more agressive than just Eligard. You should check out the website Us too, as well as some other websites on advanced prostate cancer and on hormone resistant prostate cancer. The folks there are extremely knowledgable.
After 9 months, my husband's PSA is undetectable and his tumors have shrunk dramatically. Based on all the tests, his specialist went as far as giving the prognosis that he should be able to be with us for at least another 5-10 years.
So really, don't give up yet, there is still hope. Help your father researching PCa because the information can be overwhelming. Stay strong, Dutchy
7/6: PSA 1,946, multiple bone metastases in thoracic, lumbar spine, pelvis, bilateral ribs and proximal left tibia, 2 weeks Casodex (50 mg)
25/6: PSA 407, Lupron injection (22.5 mg) + Zometa (4 mg IV)
20/8: PSA 3,7
24/9: Started 50 mg Casodex daily
29/9: PSA 0.7
30/9: Lupron injection (22.5 mg) + Zometa (4 mg IV)
14/10: PSA 0.17
18/13: PSA 0.003, Lupron injection (22.5 mg), Testosteron 0.6