Best time for first post-op PSA?

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FairRider
Regular Member


Date Joined Jan 2008
Total Posts : 32
   Posted 4/7/2008 9:38 AM (GMT -7)   
Hi -

We will soon have our 1st post-op PSA and on our surgeon's instruction we read 2 things - Have it done at 4 weeks and have it done 6-8 weeks.

From experience her, how long does it take after surgery to impact the blood test? If its too early, could there still be PSA leftover, which would then give a worrisome read?

Thanks everyone!

FairRider
Age 54; (Father, paternal uncle and 1 brother so far with Pca)
1999 PSA 2.8; 2004 PSA 2.88; 1/2008 PSA 5.6 & repeat 4.37
DRE - "Unremarkable, L side slightly larger"
Free PSA 0.46 and ratio 0.11
Biopsy 1/25/2008 - 10 Cores - 4 with adenocarcinoma
3 cores Gleason 3+3=6 and 1 core 3+4=7
No Stage given on report, maybe T1c or T2c ?

Robotic Surgery March 17, 2008
Both Nerves Spared - Pre-surgery DRE - TC1
Post Op Pathology - T3a Extra-prostatic Extension,
CLEAR margins, 4 Lymph Nodes Clear, Seminal Vesicles clear.
Gleason now 4+3+7, Tumor 20-30% of gland
Dry immediately! - no pads by day 9 Post-op
No response with Viagra, minimal with Bimix


hawkfan75
Regular Member


Date Joined Jan 2007
Total Posts : 165
   Posted 4/7/2008 10:07 AM (GMT -7)   

FairRider,

As you mentioned, it does stay in your bloodstream for awhile.  It has a "half-life" and needs time to work its way out.  While your doctor should be the final word, I was told to wait until the 6-8 week mark to make sure you get a true reading.  I would hate to get upset over a false positive reading.  It sounds like you're doing great with the continenence issue, so I would just keep walking and healing right now.  Think positive thoughts and get the PSA test at 6-8. 


Age 57 at diagnosis,  PSA 4.7 (up from 3.2 one year ago)
Biopsy November 8, 2006 1 of 10 cores positive 5% LEFT Side Gleason 3+3
Robotic surgery January 19, 2007
Post Surgery Pathology Stage T3a, Gleason 3+4, positive margins and capsular penetration RIGHT Side
Post Surgery PSA:  March 5:  0.01
5 month PSA, June 13, 2007:  0.08
Adjuvant therapy began June 26 with Zoladex injection
Radiation began August 23, ended October 8
First post radiation PSA, December 18, 2007:  0
 
 


Lungman
Regular Member


Date Joined Jan 2008
Total Posts : 276
   Posted 4/7/2008 10:26 AM (GMT -7)   
My first post op PSA was at 3 mos and the second was at 6 mos. My understanding is that 9 and 12 mos are upcoming. I agree, having one done too soon would only create anxiety if you still had detectable levels, which would likely be not from new or existing PCa, but from pre-surg levels.
Pre-Op PSA 9.9
1 of 12 cores positive, Gleason 3+3
DaVinci on 9/5/2007
Post-Op Gleason 3+6, Negative Nodes and Margins
Less than 1% of prostate involved with CA
3 Month PSA 0.01, 6 Month PSA 0.01
Incontinence resolved 9/15/2007, one day after cath removal
ED showing significant improvement, more notable over last month
with Viagra 100 mg.


Frank1205
Regular Member


Date Joined Feb 2008
Total Posts : 308
   Posted 4/7/2008 12:41 PM (GMT -7)   

Hi Fairider,

I have a 6 week post op follow up and then at 3 months at this time.

Frank

 


Diagnosed 01-08-08 @ 53 years old 
DRE normal - High PSA for 5 or more years
2004 Biospy negative - 2008 Biopsy positive (01-08-08)
10 cores, 1 positive and at 1% of that one core
Current PSA 6 - Bone and Ct scans negative
clinicalg Staged at T1C - Gleason 3+3 = 6
Robotic Da Vinci performed March 27th, 2008
University of Chicago
5 hour surgery , 3 hour recovery
Unexpected Cardiac issues appear and disappear?
Hospital stay 30 hours - Catheter out in 7 days  normaly expected leakage - Erectile funtion back on line 9 days 
Post Pathology T2C, Gleason 7, 10 % of both portions of prostate, Seminal vessels clear, fat tissue clear,Tumor on bottom of prostate distal, 1 positve margin distal at penis, going to meet with oncologist to discuss treatment options if any at this time.
 


Magaboo
Veteran Member


Date Joined Oct 2006
Total Posts : 1210
   Posted 4/7/2008 12:54 PM (GMT -7)   
I also had my first PSA test result 3 month after the operation and I will have additional tests every 3 month for 2 years. After that, if the PSA level stays very low, I'll have the tests every 6 month for life (?). It's hard having to wait for the first test result, but at least you'll know that after 3 month all the residual PSA should have worked its way out of your body. Unfortunately, I found that the wait for these test results doesn't get any easier as time goes by. Just one of the down sites to this darn disease.
Wishing you a full and speedy recovery.
 
Magaboo

Born Sept., 1936
PSA 7.9
Stage T1C
-ve DRE
Gleason's Score 3+4=7
2 of 8 positive
Open RP 28 Nov 06
Post op staging T3
Gleasons still 3+4=7
Seminal vesicles and lymph nodes clear
Catheter out 15 Dec 06
Dry since 11 Feb 07
All PSA tests in 2007 (4) <.04
PSA test Mar., 08 =.04 
 
 


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 4/7/2008 2:05 PM (GMT -7)   
Mine was less the two weeks after surgery. I wasted no time in retaining an oncologist and he started them right away. There should definately be a drop Here's my history:

October 3, 2006 19.8 (1st PSA)
October 10, 2006 18.9
November 27, 2006 13.9 (Dx via biopsy)
Surgery February 16, 2007
February 28, 2007 0.9 (via Oncologist)
March 12, 2007 0.1
March 23, 2007 <0.1 (first undetectable) NADIR
May 16, 2007 <0.1
July 18, 2007 <0.1
September 19, 2007 <0.1
January 29, 2008 <0.1
 
Next test : May 13, 2008
 
 
Tony


Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology: Gleason 4+3=7, positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (1/08): <0.1
I will continue HT until May '09. 
Years in Remission (3/23/07): 1
Visit my Journey at:
 
STAY POSITIVE!
 
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