PSA Fluctuations

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Ken S
Regular Member

Date Joined Nov 2006
Total Posts : 120
   Posted 4/23/2008 7:31 AM (GMT -6)   
After having PSA numbers at or below 0.01 for a year in March my PSA went up to 0.04 and last week again 0.04. I realize these are still very good numbers but my thoughts/questions are: Before a PSA blood test it is advised that you abstain for any sexual (ejaculation) and strenuous activities for 48 hours, does this pertain to those of us who have had a prostatectomy?

After a year and a half (and a few pounds) of inactivity I joined the Y and started playing racketball again, bought a new bike (petal power) to get back in shape, all this after my PSA test (0.01) last November, can this cause a PSA rise. Also can there be a bounce from adjuvant radiation treatments or is that only from primary radiation treatments?

My oncologist said he was a little concerned about recurrence, my GP said it's too early to worry about it.
Age 54 (2006)
PSA - 2005 - 3.2, 2006 - 3.7
Biopsy 8/06, Gleason 6 (3+3), T1c
Radical Retropubic Prostatectomy 11/3/06
Post-Op Biopsy, still Gleason 6 (3+3),
T2c, right apical margin positive
CT Scan 1/07, tumor discovered on right
kidney (unrelated to PCa)
Partial Nephrectomy 3/9/07
IMRT (37 Treatments) started 4/23/07
PSA 11/07 - less then 0.01

Mike A
Regular Member

Date Joined Feb 2007
Total Posts : 213
   Posted 4/23/2008 7:43 AM (GMT -6)   
I've never heard of exercise or radiation, causing a rise in PSA. I agree with your GP, 0.04 is still well within the non-detectable range. I know it's hard to ignore any rise in the numbers, but sometimes I think they carry the decimal range out too far.
June 2005 - Age 53 PSA 4.8 at regular physical October 2005 - After several rounds of anti-biotics, PSA 5.2 at Urlogist November 2005 - Biopsy negative July 2006 - PSA 5.9 at regular Physical October 2006 - After several more rounds of anti-biotics PSA 8.1 November 2006 - Second biopsy - Positive December 2006 - Gleason (3+4=7), Tumor T1c, CT Scan and Bone Scan Negative
January 2, 2007 Robotic Prostatectomy, University of Rochester Medical Center - Tumor confined but larger than thought, only one nerve able to be spared. Margins clear. February 2007 - Three to fo ur pads a day, no erection with viagara. April 2007 - First Post-Surgical PSA 0.02. Down to one pad a day.July, 2007 - Six Month Post-op: PSA 0.04 No change in ED. October, 2007 - Nine Month Post-op: PSA back down to 0.02!Almost totally dry! Only slight improvement in ED - Will try injections if not improved by next appointment. January 2008: One Year Post-OP PSA 0.02 still dripping, but improving. Tried 500 dose of MUSE for ED, no luck. Will try 1000.

Veteran Member

Date Joined Apr 2006
Total Posts : 1732
   Posted 4/23/2008 2:43 PM (GMT -6)   

NO, you can have sex any ole time you want to these days !!! It will not influence your PSA but it will make your day much better :>)

I agree with your Doc's...both of them. Too soon to be worried yet, not far enough out to relax. It's all aobut trends Ken. Is there one?? Well, not yet anyway. A positive margin says extra cautious. Your Doc is doing just that in checking. He'll check a bit more often (as he should) to see if there is an upward trend. May be nothing more than your own nadir. It isn't unusual for a man's PSA to ping a up and down a little or go up slightly and stay there forever. Let's all hope this is all it is. Robotic assisted and Lap. procedures sometimes leave behind a smidge of prostate tissue. I'm guessing any surgery could leave organ tissue.

Be Well, Swim

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