Question for Salvage radiation verterans or other informed readers

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Regular Member

Date Joined Jul 2007
Total Posts : 86
   Posted 4/23/2008 3:05 PM (GMT -6)   
After salvage radiation what is the average period of time to psa nadir.  I have read that it is between 6 and 18 months on external radiation to the prostate as the primary treatment but can't find anything on averages for salvage radiation.  Input appreciated.
DX 8/05 Gleason 5, Mayo clinic Second Opinion Gleason 6, PSA 2.8
Da Vinci surgery Dr. Dasari, Centennial Nashville 9/24/05
Pathology Report Gleason 6, 15 % on left side only very near to the edge of capsule, too close to call on margins, doc's said to watch it very closely, final decision T2A
PSA's have basically ranged from <.04 to .05 for two years.
no E.D. and no Incontinence, feel very blessed
PSA Nov 07 = .06
PSA Dec 10th 07 =.07
PSA Jan 4th 2008= .1
Started Guided IMRT on January 7th, 2008 to treat prostate bed and lymph nodes
PSA April 18th 2008 =.03

Doting Daughter
Veteran Member

Date Joined Aug 2007
Total Posts : 1064
   Posted 4/23/2008 6:46 PM (GMT -6)   
Great question! I am curious about this too, however, my father is on HT, so I don't know if his PSA will necessarily be accurate, but we will take all the O's we can get :)

What about you other guys out long did it take your PSA to drop following salvage radiation?

Father's Information
DX July 15, 2007
Age 62 (now 63)
PSA 5.5
Original Gleason 3+4=7
Post Surgery Gleason- 4+3=7
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin
One positive node
Bone Scan/CT Negative (Sept. 10, 2007)
T3a N1 M0
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07
Lupron beg. Dec 03, 2007 2 yr
Radiation started March 03-April 22, 2008- 8 weeks 5x a week
8 weeks of radiation down!!!
Praying for a cured dad. First PSA 3 months!


Post edited to single space signture...

Post Edited By Moderator (bluebird) : 4/26/2008 9:43:43 PM (GMT-6)

Regular Member

Date Joined Sep 2006
Total Posts : 187
   Posted 4/23/2008 8:12 PM (GMT -6)   

I'll be curious to see the responses... I was on hormone therapy for 6 months concurrent with salvage radiation--- so my first PSA a few months after treatment radiation was undetectable...

It took about 6 months for the hormone block to wear off, so I'm not sure my PSA at undectable 6 months ago  means a whole lot--- getting checked in 3 weeks --- hoping/praying for undectable then!

Age 47 - pre-surgury PSA 39
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
PSA as of November 29, 2007 undetectable
Next PSA May of 2008

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