Well, I am a test case study of one. My doc is willing to let me try different approaches. I kept notes on doses and results, all the way back to the first Caverject Impulse, and the lowest Caverject I took was 5mcg. Notes said it was somewhat reduced as far as pain and aching was with almost good enough erection quality, compared to the 10,15 and 20mcg doses previously. I figure with the Bimix there and just a little bit of Alprostadil that I can enhance the power of the bimix, while maybe requiring less of a dose, with no pain and aching. Time will tell, should be here tomorrow.