Terminology & Definitions

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Regular Member

Date Joined May 2008
Total Posts : 27
   Posted 5/20/2008 3:46 PM (GMT -6)   
Thanks again for you response to my other post.
Is there central site on this forum for definitions of some of the terms used?
I went though several posts and came up with some terms or references I am not familiar with.  They include:
Margins            - Used with a comment like "Negitive nodes and margins" or
                        "Cancer contained in prostate, no margin"
BiMix aka Bi-Mix - Used with a comment like "Sucess with BiMix
IMRT               - The "IM" part, RT presumably raditation therapy
Wet                - Guys refer to being "wet" after surgery not certain what they meant -                        they also reference being "dry" after some period of time
VED aka VED Therapy - Term is used in conjuction with correcting ED after RP
HT                  - Used with a comment like "HT began June 1 with Lupron & Casodex"
Thanks all-
PSA:      9.95
Gleason: 7 (3/4)
CT:        No mets indciated beyond Prostate 

Regular Member

Date Joined Apr 2008
Total Posts : 65
   Posted 5/20/2008 5:00 PM (GMT -6)   

Here's what I know--

HT --Hormone Therapy used to stop testosterone production(Lupron and Casodex are 2 of the drugs used)  wet--incontinent   dry--no longer incontinent   margins--the edges of prostate are clear of cancer if it says margins clear

I may be wrong about margins, but I am pretty sure.

IMRT is short for Intensity Modulated Radiation Therapy. The intensity of the radiation in IMRT can be changed during treatment to spare more adjoining normal tissue than is spared during conventional radiation therapy. Because of this an increased dose of radiation can be delivered to the tumor using IMRT. Intensity modulated radiation therapy is a type of conformal radiation, which shapes radiation beams to closely approximate the shape of the tumor.

Karen--New York
Husbands Info:
Age of diagnosis--62
2/28/08--PSA 279   DRE--positive/rock hard
Flomax and Casadex started
Biopsy--3/7/08--187cc--Gleason 10--12 of 12 positive--Perineural and LV invasion identified
T4 bone met.--hydroureteronephrosis/right kidney
3/28/08--Lupron Inj. started
4/7/08--Zometa IV started

Regular Member

Date Joined May 2007
Total Posts : 89
   Posted 5/20/2008 5:22 PM (GMT -6)   

Margins refer to the area immediately adjacent to the prostate but outside of the actual organ itself. Positive margins are not good as that means the PCa has escaped the capsule of the prostate.

BiMix refers to a 2 part compound of chemicals injected into the penis to acheive erection. A related topic is TriMix.

IM is the Intensity Modulated. A Google search on IMRT will explain the term.

Dry/Wet would refer to continence or lack of same. A big issue for some.

VED is a vacuum erectile device or a pump to help restore and maintain blood flow.

HT is referring to Hormone Therapy.


54 years old

PSA 5.6 on 3/20/07

DRE: Negative

Biopsy on 4/20/07 

Results 4/25/07:

3 out of 12 cores positive, 2 on the right lobe with 5% adenocarcinoma Gleason 3+3, 1 on the left lobe 10% adenocarcinoma Gleason 3+4, overall Gleason graded 7 Cancer T1C.  After web research discovered Proton Beam Therapy and called Loma Linda. Completed consultation with Dr. Luu on 7/5/2007 and started treatment at Loma Linda on 7/26/07. Completed treatment 44 on 9/28/07. 0 treatments remain. Side Effects remain minimal. 1st PSA result on January 28th is 1.1.

Regular Member

Date Joined May 2008
Total Posts : 27
   Posted 5/20/2008 5:25 PM (GMT -6)   
Thanks again!

PSA:      9.95
Gleason: 7 (3/4)
CT:        No mets indciated beyond Prostate 

Regular Member

Date Joined Jan 2008
Total Posts : 338
   Posted 5/20/2008 5:40 PM (GMT -6)   
Someone correct me if I am wrong but the margins, I believe, refers to the outside edges of the tissue that was removed during surgery.  Clear margins inplies that the material/flesh on the outside edges of that which was removed shows no signs of cancer.  You can only have margins if you have had surgery.
Richard yeah tongue yeah
Retired USAF Richard & Debbie on The Shores of Toledo Bend Lake Louisiana
Biospy 1/10/08 Gleason 10, Stage T1C  8 of 12 samples positive all Less Than 5% 
U of Florida Proton Therapy Institute
5/2/2008 LUPRON & Casodex
IMRT to start 5/16/2008 for approx 4 weeks with Proton to follow for approx 4 weeks
Turn Stumbling Blocks into Steping Stones and Keep Smiling
Our Journey is on WWW.GLEASON10.COM

Veteran Member

Date Joined Apr 2008
Total Posts : 847
   Posted 5/20/2008 5:41 PM (GMT -6)   

Bimix: A low-cost mixture of two drugs injected directly into the penis. (Papaverine and Phentolamine.) They relax the muscles that allow blood flow into the penis and so create an erection. Trimix and Caverject add a third drug to the mixture.

VED: Vacuum Erection Device, or pump. A tube that creates a partial vacuum around the penis, encourages blood to flow into it and so create and erection. Once erect, a constriction ring stops the blood flowing out again, which it can do very quickly!

Margins: Surgeons like to take some extra tissue from around the prostate along with the prostate itself. These are the margins. If the margins are clear or negative, it is good sign as it indicates the PCa has not extended into them and probably not beyond them. Positive margins, despite the term, are not so positive -- they mean that PCa is in the margins, and may have spread beyond them.


Age 63. Other than cancer, in good health; BMI 20
Pre-op: No symptoms; PSA 5.7; Gleason 4+5=9; cancer in 4 of 12 cores
7 March 2008, RRP, non nerve sparing
Two nights in hospital; catheter and staples out after 7 days
Continent, no pads needed from the get-go
Post Op: Stage pT2 M- N-; clear margins and lymph nodes; Gleason 4+4=8; prostate weight: 37gm
6-week PSA: 0
No erections (of course!)
Experimenting with VED and Bimix

Veteran Member

Date Joined Sep 2006
Total Posts : 741
   Posted 5/20/2008 7:11 PM (GMT -6)   
IGRT is Image Guided IMRT. 

August of 2006, PSA up to 4.2 from 2.7 one year ago. 
October free and total PSA 12% free and 5.0 total.
A month, or so later, 4.7.
Late in the year decide on Image Guided IMRT.
Begin 43 treatments on January 23, 2007 and finish on March 23.
Four month post treatment PSA is 1.9.
Seven month PSA is 0.8.

Doting Daughter
Veteran Member

Date Joined Aug 2007
Total Posts : 1064
   Posted 5/20/2008 7:34 PM (GMT -6)   

I think this should pretty much cover most of them! If you click on the second thread to the top, there are a number of helpful sites.

Go Ducks! :-)
DX July 15, 2007. PSA 5.5
Age 62 (now 63)
Original Gleason 3+4=7, Post-Op Gleason- 4+3=7,
DaVinci Surgery Aug 31, 2007
Focally Positive Right Margin, One positive node. T3a N1 M0.
Bone Scan/CT Negative (Sept. 10, 2007)
Oct. 17 PSA 0.07
Nov. 13 PSA 0.05
Casodex adm. Nov 07, Lupron beg. Dec 03, 2007 2 yrs
Radiation March 03-April 22, 2008- 8 weeks 5x a week
Praying for a cured dad. First PSA 3 months!

Veteran Member

Date Joined Nov 2006
Total Posts : 883
   Posted 5/20/2008 10:57 PM (GMT -6)   
I like to say "Leaker"!!!! instead of wet. I normally do not feel wet but I can almost always feel when I Leak. Of course, I'm kinda of an expert at the leakin bit.
My problem is I almost do not remember what it is like Not to wear a Pad!
Good Luck,
    43 at Dx and Surgery
    PSA 5.7, Biopsy 3 of 12 positive (up to 75%) all on left side of prostate, Gleason 7
    RRP on Oct. 17, 2006 - Nerves on right side saved. All Lab's clear. 
    Cathiter in for 28 days due to complications in healing. Removed Nov. 9, 2006
    First Post op PSA on Dec. 11, 2006  Undetectable 0.00.
    ED workable and usable with Viagra.
    Feb. 20th, 2007 - Feb. 4th, 2008  Cystoscope, Two Collagen injections,Second Opinion Consultation for Incontinance at OU Medical Center, Bio-Feedback training, Chiropractic, Accupuncture  to try to resolve ongoing incontinance (4-6 pads a day)  All PSA's 0.00.
    Feb. 22nd, 2008 - Surgery to install the AMS AdVance Male Sling.
    March 27th, 2008 - Sling not working, Little or no improvement.
    April 18, 2008 - Collagen injection.  Back to using 4-6 full pads a day within a week.
    May 14, 2008 - Another collagen injection to try to Band-Aid the leaking for our June cruise.  Will start making conusultation appiontments for AUS after we return.

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