Interesting sometimes how things flow at this site then you see what others talk about
A customer of mine is 61. His PSA has been above 6 for ten years. Fluctuates and was even recently in double digits. He just did another PSA and is awaiting the results. His first biopsy was negative. He has declined additional ones but might be headed that way again. Small world of discussion. He will hear more in the coming days if he will biopsy again.
Tom you also mention other glands that produce PSA. This is correct information though I'm not sure exactly what the affect on PSA is. Diana mentions adrenal glands that this may be a source. Adrenal glands do produce high amounts of DHT (dihydrotestosterone) that is easily converted to testosterone by PCa cells. This is why while on HT we will usually take Casodex, a GNRH, blocker that suppresses androgens sourced from the adrenal glands, to go along with Lupron, a clinical castration drug.
It is possible that he produces a significantly larger amount of DHT in the adrenals that cause higher PSA readings. It i salso possible that his PCa has missed the needles. At some point, a more detailed biopsy should be done.
I sure wish I could go back to the days where I knew nothing about
this stupid disease.!
Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007 @ The City of Hope
Post-Op Pathology: Gleason 4+3=7, positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 9 '08): <0.1
I will continue HT until May '09.
Years in Remission (3/23/07): 1
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Prostate Cancer Forum Moderator