6 months post radiation PSA

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Veteran Member

Date Joined Jun 2007
Total Posts : 789
   Posted 7/22/2008 9:59 PM (GMT -6)   
Hi everyone, my latest PSA came back 0.5 up from 0.4 , I know a lot of people on this forum would be real happy with this figure, but I am wondering where I am headed now?
Seeing doc next Wednesday.
Regards Mal. 
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7  right side tumour adenocarcinoma stage T2a
RP on 30th July,
Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck, free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.
Post op PSA 0.5 26th Sept.
PSA 23rd Oct.0.5 seeing Radiation Onocologist 31st Oct.
Started radiation treatment on 5th Dec, to continue until 24 Jan. 08.
Finished treatment, next PSA on 30th April.
PSA 30th April 0.4

Regular Member

Date Joined Feb 2007
Total Posts : 122
   Posted 7/23/2008 6:21 AM (GMT -6)   
My 3moth post radiation was 0.1 at 6 months it was 0.14 I go for my 9 month in 3 weeks, sometimes the psa will do that. good luck on your appt with your Dr

50 years old
gleason 3+4=7 psa5.8 clinical stageT3a
Da vinci surgery April10 2007 Mayo clinic Rochester, Mn.
extraprostatic extension Gleason -same
pelvic lymph nodes -negative
Catheter out April 19
37 treatments IMRT ended 10/26/07
psa Jan 29 2008 0.10
psa april 30 0.14

Veteran Member

Date Joined Jul 2008
Total Posts : 637
   Posted 7/23/2008 6:59 AM (GMT -6)   
Soon after radiation, there is sometimes, what they call a "bounce" in the PSA.. It may go up some and then go back down. There is quite a bit of information online about this. I wouldn't worry...Di
Husband Pete
dx Jan 2001 age 67 gleason 4 + 3 PSA 16.5
seed implant and conformal radiation Lupron from Jan 2001 to Jan2002
2005 Dec PSA began to rise from .5 to 8 within 6 months
Salvage surgery at MSK 9/06
Fistula operation 2/07 MSK
Many cystoscopies and ER visits with strictures
catheter for one year....Catheter taken out Sept 07..
Total Incontinence since then....
PSA .52 3/07
In line for AUS possibly in Sept 08

Veteran Member

Date Joined May 2008
Total Posts : 1010
   Posted 7/24/2008 8:54 AM (GMT -6)   

Hi Mal,

The link is to a web site called PSA Rising and the article addresses the PSA and the "bounce" seen after radiation treatment. Essentially the longer it takes to reach a nadir and the lower the nadir the better the result.



Age 58
PSA 21.5 (first and only test resulted from follow up visit to emergency room for kidney stone. first time for kidney stone too)
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear
Chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Lupron injection on May 15 and every four months for next two years
Starting IMRT/IGRT on July 7, 2008. 45 treatments scheduled

Regular Member

Date Joined Jul 2008
Total Posts : 50
   Posted 7/30/2008 11:03 PM (GMT -6)   

I am 57 and was told two days ago that my biopsy came back with 2 of 12 cores show cancer.  Of the two cores, one was 3+4 and the other was 4+4.  In each core they were around 14%.  I've read articles, forums, talked to docs, and I'm just not sure what to do.  It seems that for me, the more information I get the more confused I become.  I simply am phobic about general anesthesia so most of my confusion is probably me trying to convince myself that there is a better way.  I was pretty much settled on IMRT but my docs haven't said anything to my about hormones.  The original urologist, who is a surgeon, recommended surgery because of my age. The only thing I've read so far that has me really concerned is what options - other than hormonal therapy - do I have should my psa go up in a few years?  It sounds like there isn't anything I can do due to the scares caused by the radiation.  Am I missing anything here?  Is there something that could be done IF the cancer came back in 10 years?  Also, is the hormonal treatments palative or can they also cure the cancer?

Between  Cyberknife, Proton, DaVinci, HIFU, Radical, IMRT, IBRT, Brachia(sp), Hormones, I feel a little overwhelmed.

Help! :/

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 7/30/2008 11:36 PM (GMT -6)   
First off take a deep breath. Sometimes planning can be very stressful, but you need to look at the pros and cons of each treatment option. They are different decisions in each and every case and yours is no exception. I am a believer in positive thinking. And the best way to get there in cancer treatment is with knowledge. You have to look at treatment options in two ways ~ localized or systemic. You should be looking at localized treatment for high risk of relapse patients. This may include hormone therapy and it may not. If you choose a surgery option you have to accept that general anesthesia is a must. My experience was uneventful. If you choose a radiation option you may avoid general anasthesia, but would likely have less options later. But studies show that you can fare just as well. Cyberknife and HIFU are relatively new and still are under scrutiny. That does not mean they don't work, but your Gleason grade may indicate a different option. More proven are the radiation options and surgery, and you can still have hormone therapy later in all options. I have been through the gambit of surgery, radiation (IMRT) and hormone therapy. HT was the worse of them, but I can still tolerate it. As I've said to many, get a good doctor, a second opinion, and consider a multi-faceted major cancer center. Sometimes a combination works better than a single treatment.

We all felt overwelmed at some point. You are just two days into this and I know you are "cramming" right now. You don't have to learn it all in a couple days. Take your time and Stay Positive. You have many, many good days ahead.


Age 46 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007 @ The City of Hope
Post-Op Pathology: Gleason 4+3=7, positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 9 '08): <0.1
I will continue HT until May '09. 
Years in Remission (3/23/07): 1
Visit my Journey at:
And at:

Post Edited (TC-LasVegas) : 7/30/2008 10:39:28 PM (GMT-6)

Regular Member

Date Joined Apr 2008
Total Posts : 35
   Posted 7/31/2008 4:34 AM (GMT -6)   


  I have a very similar profile to you, my psa level at three months post op. was .4, I was then offered a trial of chemo (six sessions of taxotere).After four doses of chemo my psa is now .2. My doctor has told me that no further treatment is necessary unless my psa goes above .5.



Dx 10/12/2007 after rise in psa level to 4.7
Biopsy 7 out of 12 cores positive.
Gleason 7 3+4.
Da Vinci 4/02/2008
post op pathology positive margin gleason 7 4+3.
Staged t3a
nerves saved one side
continent from day one can't say the same about ed
still not able to achieve an erection, but close using cialis.
three month post op psa .3 (ouch)
Enrolled in clinical trial for chemotherapy 18/04/2008 using
Taxotere 75mg/m2 every three weeks for six sessions.
Waiting to see results of first psa test after chemo.
18/04/2008 - psa .4 1st chemo
09/05/2008 - psa .3 2nd chemo.
30/05/2008 - psa .3 3rd chemo.
20/06/2008 - psa .2 4th chemo.

Regular Member

Date Joined Feb 2008
Total Posts : 25
   Posted 7/31/2008 7:21 AM (GMT -6)   
              Glad to hear your psa has responded to chemo, my psa reading 3 months post op was aslo .3 my doctor advises wait and watch, a rise above .5 and I guess its RT not something I look forward to. My doctor says he has other patients that have stayed below .5 for years after rp without tratment which means that if its not cancer it must be prostate tissue. I have not seen any other pc sufferers on here or any other website where their psa level has stabilised at .5 for years after rp without any treatment. any comments ?
diagnosed pc Nov 2007 after small lump
found during routine examination
gleason 7 (3+4 ) psa 4.6.
Da Vinci Jan 2008.
post op pathology report gleason 7 (4+3)
positive margin right side nerves spared.
no incontinence problems.
ed is a problem.
psa 3 weeks post op .5
psa three months post op .3
wait and watch possible rt.

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