perineural invasion by itself is insignificant, by todays path. standards. This usually only means that the cancer has extended into the nerve canals INSIDE the prostate, and have no relation to the exterior, attached nerve bundles that provide erections. The perineural nerve canals provide a space for the cancer to grow into, and the cancer will take the path of least resistance. Unless the cancer extends beyond the margin, which is the outer most gland and tissue that is being removed, then there's little risk. I had the same thing, and that's how it was explained to me, and told not to worry about
Here's a couple links to help you understand it better:
These provide a fairly easy to understand laymans description of the prostate testing and interpretation of the path. report
Co-Moderator- Prostate Cancer Forum
4/19/07 PSA 7.6, referred to Urologist, recheck 6.7
7/11/07 Biopsy- 16 core samples, size of gland around 76 cc. Staging pT2c
7/17/07 Path report: 3 of 16 PCa, 5% involved, left lobe , GS 3/3:6.
9/24/07 (open) Retropubic Radical Prostatectomy performed
9/26/07 Post-op Path Report: GS 3+3=6 Staging pT2c, 110gms, margins clear
10/15/07 ED- begin 50mg Viagra and Vacurect pump nightly, Fully continent
1/14/08 Caverject started/stopped, aching. 2/24/08 .5ml Bimix started-success
7/31/08 ED- Viagra, pump continues, no response- Trimix .10ml x 2 weekly continues
Post Surgery PSA's: 3 mts-0, 6 mts.-0, 9 mts.-0.