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Regular Member

Date Joined Feb 2007
Total Posts : 122
   Posted 8/6/2008 6:19 AM (GMT -6)   
Anyone  taking avodart for lowering psa after surgery/radiation.
A friend of mine was put on it after his psa rose for the 2nd time post surgery and radiation
50 years old
gleason 3+4=7 psa5.8 clinical stageT3a
Da vinci surgery April10 2007 Mayo clinic Rochester, Mn.
extraprostatic extension Gleason -same
pelvic lymph nodes -negative
Catheter out April 19
37 treatments IMRT ended 10/26/07
psa Jan 29 2008 0.10
psa april 30 0.14

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4840
   Posted 8/7/2008 7:43 AM (GMT -6)   
Seems a bit strange to me to be taking the meds....
From Avodart's web site:
Indication and Important Safety Information about AVODART® (dutasteride):

AVODART is used to treat urinary symptoms of Enlarging Prostate, and to reduce the risk of acute urinary retention (AUR) and prostate surgery. AUR is a condition, possibly requiring surgery, where the prostate is so enlarged that it completely blocks urine coming from the bladder. Only your health care provider can tell if your symptoms are from Enlarging Prostate and not a more serious condition, such as prostate cancer.



Age 53   - 5'11'   205lbs
Overall Heath Condition - Good
PSA - July 07 & Jan 08 -> 1.3
Gleason - 6
(biopsy done March 4, 2008-> 2 of 12)
06/25/08 - Da Vinci robotic laparoscopy

Veteran Member

Date Joined Jul 2008
Total Posts : 981
   Posted 8/7/2008 8:17 AM (GMT -6)   
mgl said...
Anyone taking avodart for lowering psa after surgery/radiation.
A friend of mine was put on it after his psa rose for the 2nd time post surgery and radiation

I took it prior to my saturation biopsy to reduce the size of the prostate. Smaller it is, the less needles needed. I never heard it having any effect on reducing psa, other than a slight drop maybe by reducing the glands size.
Diagnosed 10/08/07
Age: 58
3 of 12 @5%
Psa: 2.3
Size: 34g
3D Mapping Saturation Biopsy
1 of 45 @2%
28g after taking Avodart
Catheter for 1 day
Good Candidate for TFT
(Targeted Focal Therapy)
Cryosurgery(Ice Balls)
Clinical Research Study
TFT performed at University of Colorado
Medical Center at Denver Fitzsimmons Campus
Catheter for 4 days
Slight soreness for 2 weeks but afterward
life returns as normal
Psa: .32 

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 8/7/2008 11:35 AM (GMT -6)   
Avodart and Proscar are commonly used in a process called triple androgen blockade or ADT3.  The same logic that Avodart shrinks a normal prostate is considered useful that it can shrink cancerous prostate cells as well.  Snuffy Myers book is based on diet and triple angrogen blockade, as is the practice by Bob Liebowitz.
Proscar - chemical name - Finasteride
Avodart - chemical name - Dutasteride
Bob Liebowitz study...Using Finasteride with HT...
Myers Article...
Both have shown the ability to lower PSA post RP.  There is also evidence that Finasteride can be used to maintain low PSA levels when using intermittent hormone therapy (IHT) during the periods that LHRH and GNRH agonists are stopped. 
Another study is being expolred the is testing using Finasteride as a preventive or delaying agent in people with high risk of getting prostate cancer ~ African American or heredity cases. 

Age 46 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007 @ The City of Hope
Post-Op Pathology: Gleason 4+3=7, positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 9 '08): <0.1
I will continue HT until May '09. 
Years in Remission (3/23/07): 1
Visit my Journey at:
And at:

Post Edited (TC-LasVegas) : 8/7/2008 11:01:58 AM (GMT-6)

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