I just joined!! Been researching about perineural invasion. Saw some posts on the mesage board but had some more ?'s. Below is my brief history, then my questions. Thanks!
In May at age 36 I took a PSA test based on family history (Father, Uncle, and Brother) and it was 4.17. Went to Urologist who put me on Leviquin for two weeks. During visit did a DRE and was OK. Two weeks later did another PSA: 3.9. Suggested Biopsy which came back 6 out of 12 postive all on right side where the DRE checks! My biopsy exerience was very unpleaseant. Blood clots were very alarming and painful! It seems like hit or miss some people have no issues while others do. Then took a battery of tests CAT Scan (OK), Bone Scan (OK), Prostate MRI (OK) Not sure how I made it through this test, and Cystoscope (OK)
4 Weeks ago had the robotic (daVinci) Surgery. Post pathology came back that it was in my left side as well, which the Uroligist mentioned that it shows the biopsy is not defintive test and I was lucky it showed up on right side. My post-op pathology was a T2c, lymnodes neg, seminal neg, contained in prostate capsule. My Gleason went down from a 7(3+4) to a 6 (3+3).
Recovery: my inconsistence is getting better but I wake up in the middle on the night alot to go bath room and I dont drink anything after 7pm because if so I wake up with a bladder full and in alot of pain until it is relieved. No erections yet, on Viagra 25mg a day.
In my post op pathology report stated perineural invasion in right lobe. Have read alot about that if perineural invasion in biopsy indicator of possible it escaping the prostate capsule. Does anyone have any info what it means for me with negative margins, and contained in capsule? When I go back to Doc will ask but he seemed very happy about results that I was cured. I am very concerned about reoccurrence especially based on my age no real data I saw on 30 year results just see 5 and 10...
THANKS, and LIVESTRONG!
Da Vinci Surgery 7/2008
First PSA : 4.17 5/2008
Second PSA After 2 weeks of antibiotics : 3.9 6/2008
DRE: Negative 5/2008
Bone Scan/CAT Scan: Clear 7/2008
Cystoscope: Normal 7/2008
Prostate MRI: Normal 7/2008
Biopsy : 6 out 12 Postive all on right side, Gleason 7 (3+4).
PostOp: T2c (On Both sides), margins clear, seminal clear, nodes, clear. Gleason 6(3+3).
First PostOp PSA: 9/2008