The finite answer is yes. Gleason is not the lone prognosticating factor. in addition to all you mention, tumor size and stage are also important in predicting outcome. A contained Gleason 9 has a better outlook than my Gleason 7, for example. Post operative Gleason merely tells us how aggressive the cells are, and how the disease may behave upon relapse.
In my case my prostate was 25% cancer by volume, 70% of that tumor was grade 4, and my cancer had spread locally to facia tissue, skelital muscle, and ther was SVI. i think everybody should know where they are with these things about their disease.
Age 46 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007 @ The City of Hope
Post-Op Pathology: Gleason 4+3=7, positive margins, Extra Prostatic Extension (EPE)
Bilateral seminal vesicle invasion (SVI); Stage pT3b, N0, Mx
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (September 17 '08): <0.1 ~ Undetectable!
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