JEKNY...from what I read, that Positive margins can usually occur when the surgeon cuts across a small section of the tumor, because the tumor was close to the edge to start with. It is impossible to know "exactly" how much tumor cells were left behind, however for the most part any small amount (<3 mm) will not typically survive and will die out due to the loss of blood and the resulting scar tissue. So in most cases roughly 80% of the time it isn't a concern. In your case you had evidence of extention and that will be the area of concern and the reason for higher stage on the pathology report.
Frank's is close to the bladder and is of some concern. His doctors recommendations are inline with with what I have read about
the positive margins and the
location of the margin. The
location seems to be the greater factor in his case.
Hopefully this won't be a problem for either one of you.
Age 58 at Diagnosis
Oct 2006 - PSA 2.6 - DRE Normal
May 2008 - PSA 4.6 - DRE Normal / TRUS normal-Gland 38 cc
July 2008 - Biopsy 4 of 12 Positive 5 - 30% Involved Bilateral (Perineural Invasion present at base)
Gleason (3+3) 6 Stage T1C
August 23 - Bone Scan - Hips, Spine and ribs marked uptake - X-Ray showed clear -Hooray
Sept 9 2nd DRE - questionable - TRUS...shadow in base - Gland now 41 cc
Robotic Surgery Sept 18, 2008
Pathology October 1,2008
Gleason 7 (4+3) Staged pT2c NO MX
Gland 50 cc
Seminal Vesicles and Lymph Nodes clear
Positive Margins Right Posterior Lobe
4 tumors in prostate - largest being 6 cm
PSA Oct 08 <.05