the rising psa. 12.8 in october; then 14., 16.37 now. bone scan and cat scan negative. now the biopsy came back negative. had hormone so future psa's will be reduced but still don't know the cause of psa rise. radiation bounce ruled out - numbers too high. no infection, no inflamation. had 3 psa's done at 2 week intervals at two different facilities so it's not the testing facility. can the PC have metatasized somewhere else? the urologist was convinced the biopsy would show return of cancer but it didn't. we are at a loss. any suggestions would help.