1st post RRP PSA and question about lupron

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New Member

Date Joined Aug 2008
Total Posts : 8
   Posted 11/11/2008 12:17 PM (GMT -6)   
My father just had his 3 mo PSA after robotic surgery and it was <0.04!! We're really optimistic that it'll stay that way (thanks to everyone here for answering our questions the last 3 months). One problem is that before deciding on surgery, my father was placed on Lupron. He only had one shot and it was in April, but he's still having some "hot flashes" from it. Is it unusual to be having these side effects more than 6 months after the shot?


Regular Member

Date Joined Apr 2008
Total Posts : 270
   Posted 11/11/2008 3:14 PM (GMT -6)   
You will note from my info below that I too had a Lupron shot in April. Mine was a 4 month shot. I was surprised that it lasted well beyond the 4 months. I did not mark the calendar, but I was still feeling the effects of it into September. I have had no effects from it (hot flashes, etc.) since September. It seems strange that a 3 month shot would last that long, but I know I read from others that it took additional time for the effects to wear thin - with some people more than others. I hope he will soon be beyond it.

Age 61
Original data - pre-operation
PSA: 5.1
T1C clinical diagnosis, Needle biopsy - 10 cores, Gleason 7 = 3+4 in 1 core (40%), 7 cores Gleason 6 = 3+3 ranging from 5% to 12%
All scans negative
Lupron administered 4/9/2008 for 4 months (with idea I would undergo external beam radiation followed by seed implants - then I changed my mind).
Robotic DiVinci surgery - Dr. Fagin (Austin) May 19th
Post operative - pathology
pT2c NX MX
Gleason 3+4
Margins - negative
Extraprostatic extension - negative
seminal vesicle invasion - uninvolved
1st Post PSA <.04
2nd Post PSA <.1 10/30/2008

Regular Member

Date Joined Sep 2006
Total Posts : 187
   Posted 11/12/2008 6:15 PM (GMT -6)   

I had two Zolodex shots, 3 months apart... my hot flashes and libido loss didn't subside for 9 moths after my last shot --- so I guess that's 6 months after its effective date.

My oncologist felt that was fairly typical --- no idea if Lupron would be the same.

Age 47 - pre-surgery PSA 39
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
PSA as of November 29, 2007 undetectable
PSA as of May 14, 2008 undetectable
Next PSA November of 2008

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