Detectable... Non Detectable??

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Gene214
Regular Member


Date Joined Mar 2007
Total Posts : 422
   Posted 11/13/2008 9:15 AM (GMT -7)   
I know it has been discussed on this forum before, but I cannot remember why some psa tests reading 0.05 (like my last one) was described by my doc as "nondetectable" and a friend's (who is a member of HW but rarely visits the site any longer) psa is 0.02 and considered by his doctor to be "detectable".  Seems like it has something to do with equipment???  Yes?  No?  ?
Gene214
PC diagnosed 12-06 @ age 63
Radical open removal 2-14-07, Gleason 3+3=6
Removal of stricture 6-07, incontinence continues
Scheduled for AUS & IPP 05-08
Surgeon cancelled one day pre-surgery, due to cardiac concerns
Nuclear stress 5/13/08
3 stents 5/27
AUS, IPP implanted 07-16-08
AUS, IPP was activated on 08-18-08.  They both work!
10-20-08 went back to surgeon for a follow-up.  Both devices are working very good and surgeon was very pleased that I am very pleased.
 


Gordy
Veteran Member


Date Joined Jun 2005
Total Posts : 528
   Posted 11/13/2008 9:51 AM (GMT -7)   
Since they're both on the same scale (two places to the right of the decimal point), I'd attribute it to just differences in doctors and the fact that some of them haven't a clue.

-Les
1/2005 Dx PSA 26.5 Gleason 7 (4+3) @Age 61
1/2005 Start Casodex and Zoladex
PSA drops to <0.01
7/2005-8/2005 5 weeks of IMRT and then HDR brachy
1/2007 Rad Oncologist orders CT scan of pelvis
because of complaints of pain in both thighs
MRI confirms pain not caused by cancer BUT
1/2007 CT scan of pelvis picks up a nodule at bottom of left lung
5/2007 CT scan of lungs shows 1/2007 nodule has grown and
there are numerous nodules on both lungs.
6/2007 Thoracic surgeon removes wedge of left lung for biopsy
6/2007 Path report says 95% chance of metastatic PCa, but she's
never seen cells like this before.
8/2007 2nd opinion at M.D. Anderson in Houston.
They confirm: mutated PCa, very rare, but seen there 2 or
3 times. Recommendation: have CT scans every 6 weeks
and watch for change. At that point start chemo and will
survive for 22 - 24 months thereafter.
PSA still undetectable, but get Lupron shot to bring T down from 27
2/2008 Trip to Houston – PSA now 0.5 and nodules larger. Lupron shot.
6/2008 Trip to Houston - Finally got results from doc. A number of lung nodules have grown, but, more important to him, is the fact that the malignant lesion on my pelvis seems to have flared up and he wants me to start chemo. He said I could wait a few months, but I told him I want to start now. He to get me signed up for a clinical trial in nearby NY.
9/2008 Interim bone and CT scans show progress vs. scans done before beginning trial. I'm cautiously optimistic. Next scans 10/30/08.
10/2008Bone and CT scans continue to show improvement. Med onc attributes mostly to Taxotere/Prednisone while I believe majority of progress attributable to investigational drug, Sprycel.

Post Edited (Gordy) : 11/13/2008 9:54:48 AM (GMT-7)


Lungman
Regular Member


Date Joined Jan 2008
Total Posts : 276
   Posted 11/13/2008 10:28 AM (GMT -7)   
The undetectable refers to a value less than 0.1, which is the older standard when untrasensitive testing was not available. With the advent of newer, more sensitive testing values such as 0.01 are reported, but "undetectable" denotation remains. At least that is my understanding.
Randy
46 you when diagnosed, now 48
Pre-Op PSA 9.9
1 of 12 cores positive, Gleason 3+3
DaVinci on 9/5/2007
Post-Op Gleason 3+6, Negative Nodes and Margins
Less than 1% of prostate involved with CA
3 Month PSA 0.01, 6 Month PSA 0.01, 9 Month PSA 0.01
One Year PSA 0.01
Incontinence resolved 9/15/2007, one day after cath removal
ED showing significant improvement.
Occasional Success with Oral Meds
Success with BiMix

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