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Regular Member

Date Joined Aug 2008
Total Posts : 328
   Posted 11/24/2008 8:16 AM (GMT -6)   
Going in 3 weeks back to doc and anticipate him giving me the Injections Option...For those who have used them how is the pain factor? First being the injection itself, and has anyone had any problems where your erection lasts way too long (which I am afraid of). How long are they supposed to last? Cant imagine it being a pleasant experience lasting more then an hr...Is there a certian location it needs to go? And are there any short and long term sideffects? Thanks!!
Age Dx 37, 7/2008
First PSA : 4.17 5/2008
Second PSA After 2 weeks of antibiotics : 3.9 6/2008
DRE: Negative 5/2008
Biopsy : 6 out 12 Postive all on right side, Gleason 7 (3+4).
Bone Scan/CAT Scan: Clear 7/2008
Cystoscope: Normal 7/2008
Prostate MRI: Normal 7/2008
Da Vinci Surgery 7/2008
PostOp: T2c (On Both sides), margins clear, seminal clear, nodes, clear. Gleason 6(3+3).
First PostOp PSA 9/2008: <0.01
2nd PSA 12/2008: Praying for <0.01

Veteran Member

Date Joined Jul 2006
Total Posts : 686
   Posted 11/24/2008 11:06 AM (GMT -6)   

There is almost no pain involved with the actual injection.  The anticipation is worse than the reality.  If you are using Caverject also known as alprostadil there is often some significant aching and even worse pain for up to a few hours after. 

If you are using a formulated "bi-mix", it does not contain the alprostadil so there is usually no pain or discomfort.  Your doctor should give you detailed instructions as to how to inject and the correct spot.  If too much is used it can cause priapism (prolonged erection).  That usually means a full erection that lasts more than four or five hours. Medical attention is suggested for that problem.

One possibe downside that I have experienced is plaque build up and peyronies (curved penis) during erection.  I am dealing with the the plaque build up problem right now.  Looking for more information.

PSA up to 4.7 July 2006 , bump noted during DRE
Biopsy 10/16/06
stage T2A  -  Psa 4.7
Gleason  4+4=8  right side
DaVinci Surgery  January 2007
Post op confirms gleason 4+4=8
No extension or invasion found
No continence problems
PSA 90 day (-.01)  , (6 month -.01) , (9 month +.02) , (1 year +.02) ( 18 months +.02)
ED still a problem, minor succces with bi-mix
plaque buildup due to injections 

Regular Member

Date Joined Nov 2008
Total Posts : 122
   Posted 11/24/2008 12:07 PM (GMT -6)   
SHU93,  My experience is very much like "lifeguyd's" except I use Trimix.  Everyone has a little different result to any of these drugs, but there are some things that seem to help all of us.  I use a very small (31 guage - 5/16 length needle) which is smaller than the Dr. prescribed initially.  I just make sure it is pushed in all the way.  Little or no pain.  After experimenting with dosage, I ended up at .9ml to 1.2ml to get the desired results.  The larger the dosage the harder you get and the longer it lasts.  I also roll Mr. Happy between the palms of my hands for a few seconds to make sure the drugs get spread around.  I think this has also helps as far as scarring is concerned.  Good luck to you and hope you get the zero your looking for.  I just past the 3 yr. mark and so far still getting zeros.  Again, Good luck 
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