Any rule of thumb for how long it takes for cancer to double in size

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New Member

Date Joined Nov 2008
Total Posts : 2
   Posted 11/28/2008 6:42 PM (GMT -6)   
Just diagnosed with Gleason 6 (3+3) in one out of 12 biopsies. Any rule of thumb for what the time frame for it doubling in size?

Veteran Member

Date Joined Apr 2008
Total Posts : 847
   Posted 11/29/2008 4:28 AM (GMT -6)   
I've never heard of any rule of thumb. Your Gleason 6 is a low grade cancer, so the PSA doubling time is likely to be a period of years, perhaps many years. A more aggressive cancer might double in a period of months.

A low grade cancer might turn aggressive, then again it might not -- unfortunately there is no way of knowing in advance. This is where the active surveillance strategy has an advantage -- you monitor the cancer closely, and treat it only once it reaches a certain threshold. This avoids treating a cancer that may never need treatment.
Age 63. Other than cancer, in good health; BMI 20
Pre-op: No symptoms; PSA 5.7; Gleason 4+5=9; cancer in 4 of 12 cores
7 March 2008, RRP, non nerve sparing
Two nights in hospital; catheter and staples out after 7 days
Continent, no pads needed from the get-go
Post Op: Stage pT2 M- N-; clear margins and lymph nodes; Gleason 4+4=8; prostate weight: 37gm
6-week and 7-month PSAs: 0
Bimix injections working well 

Steve n Dallas
Veteran Member

Date Joined Mar 2008
Total Posts : 4840
   Posted 11/29/2008 6:14 AM (GMT -6)   

Spreading outside the prostate should be more of a concern....Hopefully you aren't considering waiting to do anything since it isn't going to go away by itsself.

Age 53   - 5'11"   205lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Gleason - 6
(biopsy done March 4, 2008-> 2 of 12)
06/25/08 - Da Vinci robotic laparoscopy
10/03/08 - 1st Quarter PSA -> less then .01

Surgeon - Keith A. Waguespack, M.D.

Las Colinas and Plano Offices


Regular Member

Date Joined Sep 2006
Total Posts : 211
   Posted 11/29/2008 6:45 AM (GMT -6)   

Biopsy readings are subjective, and what looks like cancer to one person might look more normal or look like a different grade to another. 

If you have not already done so, first thing to do is to have your biopsy slides sent for a 2nd reading by an expert pathologist: after that's been done to confirm where you stand, you can consider your options more fully and logically.

Everyone is different, but unfortunately most people including many doctors have thier pet theory about the best treatment option which they'll want to tell you about.

A good  idea is to do your research on the various treatment options: the best comprehensive book I've read on this subject is the publication by Lee Nelson MD, "Prostate Cancer Prevention and Cure". It covers diagnosis, stages, lifestyle changes, diet, supplements, treatment options, selecting your doctor, etc.

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