Selmer great to hear this story and isn't interesting that this doc was highly displeased that someone got great results with DES, why???? Someone stealing the cash cow of the new drugs??? Are these newer drug makers righteous ones?? Google the lawsuits on Zoladex or Lupron and how they lost and paid millions out and it never stopped them from selling them. I am not against using those drugs and they have there place as do all PCa treatments or non-treatments, I am against profitteers and the biberies and such given to doctors to use only their drugs (agenda driven by greed and profits) and by price goughing, the profits made on these types of LHRH agonists is outrageous, but welcome to the culture of greed. Guess how much Lupron costs in Spain??? A friend I met on boards says 3 month doseage amounts to maybe $400 (USA compared dollars); so are we being "marketed" to because we have more insurance and high incomes in our country???? Lupron here is many times that amount and it is also used on women for some therapies and they pay less for it also, go figure. You decide what you believe is the actual truth.
There is a Journal of Urology Article from around Nov. 2003 on the Non-steriodal effects of DES useage.... It is a fabulous read on this drug and its benefits to the patient and is one of the few drugs that can work against hormone refractive PCa, maybe not for a long time or to cure one. But when you can possibly extend your life, you might like to know your options.
As to the side effects on DES, yes I did lose some hair as you mentioned. I felt strong and pretty normal (had E.D. after prior treatments already), I got breast radiation that is available to prevent 'gynecomastia' it apparently worked pretty well, I did not wish to take the risk of keeping 'abreast' on PCa literally. That was done with electron rays and short exposure with controlled depth penetration done in one session, usually done in 3 sessions, left me with like a sunburn appearance for 1-2 months (round spots around boobs about 6" diameter, but it did go away and no problems have cropped up). The psa results on DES were excellent compared to ADT1-3 useage, so I went off of it for 2 years, I like to keep more to natural and undrugged if possible. Just started resuming it and will see how it goes within 1-2 months or so. It is not for everyone and I did not say it was. It could be an alternative for some along with alot of other drugs that are used against PCa and especially hormone refractive PCa.
Thanks for sharing that story on his DES useage, there is not alot of positive information out there on this, why???? Believe what you wish, I am going with there is no profits to be made on this and secondly if a doc prescribes it and you have major problems like a blood clot, he cannot win a possible lawsuit, so most docs won't even put themselves into that somewhat unlikely scenario. The drug is much safer today in low doseage and with coumadin and patients being pre-screened for clotting factors. There are some docs that will prescribe it and know it is useful, I would call them compassionate in the patients wishes because there is no money motive for it at all, also they would have to be open minded and have looked at things like that Journal Article I mentioned. Isn't it uncanny that $100 year drug can out perform $13000 combo drugs and does not deplete your bone density, and can actual cause direct apoptosis of PCa cells (not make them dormant but kill many of them directly). Such stuff is written in the Journal of Urology Article I mentioned, of course it is not news worthy, just as home remedies and treatments(for any medical ills) are considered worthless many times, too by the mainstream or for profit establishments.
Zufus (if you like to add the D to it, be my guest I chose the name as a fun thing anyway if you cannot laugh at yourself, you take life much to seriously, but we are allowed to have are opinions and free speech...atleast so far)