Well that was very wise to have it reviewed especially for patients whom chose one time treatment modalities towards cures. Many times when reviewed by experts pathology reveals all kinds of things that were missed (evidence is out there on such), with 18 types of prostate cancer it is very possible to not even know which one a patient actually has(it is an art and you need an artist), let alone the many other variables. Because of Partin tables, Narayan, Bluestein, nomograms and mathematical 'gigs' we take this pathology and other known numbers (psa, gland volume/size, etc. stuff) and put them into those models to seek out a possible clue as to where does one fall in the percentages or odds of the average patient who under goes certain modality/treatments. It is an averages thing you end up looking at, some would end up on either side (above or below), it is not precise science, but is used as a possible tool in PCa for consideration and has some merit. Then patients and doctors can use this type of information to make hopefully a better decision as to how to treat PCa, or atleast have a small clue as to risk and reward concept for a treatment modality.
There are actually 3 kinds of ploidity that can be found by pathology, why even bother to know???? (I believe it is something like this): The first being diploid DNA (double stranded-close to normal cell structures) responds best to hormone drugs, aneuploid (might have been like triple stranded-not quite as well for response) and a third one can't remember if it was called tetraraploid?(way crazy DNA structures-anyway it is the worst diploidity) to have and probably the patient would have a heads up knowing what they may be facing as to taking drug therapies against it (treatment risks)and/or possible survival time. I don't have my notes in front of me...but those three explained (lightly) is the guts of the matter, it is probably great my memory is even this good after seeing this stuff 6 yrs. ago or so. Not everyone needs to know their ploidity on pathology, but experts can test for such (it is additional costs) and you probably did not get this information in the original pathology that was sent out to a lab.
Now football- Lions are probably the best 'high school' team out there (LOL). Perfect season (hooray). Myself I enjoy a close game and don't get to excited about
being numeral uno and I even praise Ohio State against our two Michigan teams. If your good it is worth a watch. O-how-I hate-Ohio State (not my mantra-isn't that silly to tout out in public????) I admire good teams, luckily I did not get biased by going to MSU or M-State (my brothers went their) but they don't real care who wins anyway.
One brother has PCa for 4 yrs.+ now and doing w.w.(monitoring), the other appears clear via testing and psa's at this time, my father is unknown never diagnosed that we heard of and died of a stroke issues. My sister is the oldest and has no major medical issues we know of at this time.
Like Arnold S.- "I'll be back"
Post Edited (zufus) : 1/5/2009 4:09:12 AM (GMT-7)